Pinar Obakan-Yerlikaya
Overview
Explore the profile of Pinar Obakan-Yerlikaya including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
135
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Recent Articles
1.
Ayhan-Sahin B, Apaydin Z, Obakan-Yerlikaya P, Arisan E, Coker-Gurkan A
PLoS One
. 2022 Jan;
17(1):e0260144.
PMID: 35061691
Background: Growth Hormone Releasing Hormone (GHRH), 44 amino acids containing hypothalamic hormone, retains the biological activity by its first 29 amino acids. GHRH (NH2 1-29) peptide antagonists inhibit the growth...
2.
Ozfiliz-Kilbas P, Sonmez O, Obakan-Yerlikaya P, Coker-Gurkan A, Palavan-Unsal N, Uysal-Onganer P, et al.
Cancers (Basel)
. 2021 Nov;
13(21).
PMID: 34771486
(1) Background: Increased fatty acid synthesis leads to the aggressive phenotype of breast cancer and renders efficiency of therapeutics. Regulatory microRNAs (miRNAs) on lipid biosynthesis pathways as miR-33a have potential...
3.
Coker-Gurkan A, Can E, Sahin S, Obakan-Yerlikaya P, Arisan E
Mol Biol Rep
. 2021 Jul;
48(6):5233-5247.
PMID: 34244887
Purpose: The constitutive activation of STAT3 through receptor tyrosine kinases triggered breast cancer cell growth and invasion-metastasis. Atiprimod impacts anti-proliferative, anti-carcinogenic effects in hepatocellular carcinoma, lymphoma, multiple myeloma via hindering...
4.
Coker-Gurkan A, Ozakaltun B, Akdeniz B, Ergen B, Obakan-Yerlikaya P, Akkoc T, et al.
Mol Biol Rep
. 2020 Nov;
47(11):8797-8808.
PMID: 33130987
Active growth hormone (GH) signaling triggers cellular growth and invasion-metastasis in colon, breast, and prostate cancer. Curcumin, an inhibitor of NF-ҡB pathway, is assumed to be a promising anti-carcinogenic agent....
5.
Adacan K, Obakan-Yerlikaya P, Arisan E, Coker-Gurkan A, Kaya R, Palavan-Unsal N
Amino Acids
. 2020 May;
52(6-7):871-891.
PMID: 32449072
Epibrassinolide (EBR), a polyhydroxysteroid belongs to plant growth regulator family, brassinosteroids and has been shown to have a similar chemical structure to mammalian steroid hormones. Our findings indicated that EBR...
6.
Atiprimod induce apoptosis in pituitary adenoma: Endoplasmic reticulum stress and autophagy pathways
Coker-Gurkan A, Ayhan-Sahin B, Keceloglu G, Obakan-Yerlikaya P, Arisan E, Palavan-Unsal N
J Cell Biochem
. 2019 Jul;
120(12):19749-19763.
PMID: 31270852
Pituitary adenoma is the most common tumor with a high recurrence rate due to a hormone-dependent JAK/signal transducer and activator of transcriptions (STAT) signaling. Atiprimod, a novel compound belonging to...
7.
Coker-Gurkan A, Bulut D, Genc R, Arisan E, Obakan-Yerlikaya P, Palavan-Unsal N
Mol Biol Rep
. 2018 Nov;
46(1):355-369.
PMID: 30467667
Autocrine growth hormone (GH) signaling is a promoting factor for breast cancer via triggering abnormal cell growth, proliferation, and metastasis, drug resistance. Curcumin (diferuloylmethane), a polyphenol derived from turmeric (Curcuma...
8.
Arisan E, Ergul Z, Bozdag G, Rencuzogullari O, Coker-Gurkan A, Obakan-Yerlikaya P, et al.
Mol Biol Rep
. 2018 Nov;
45(6):2175-2184.
PMID: 30406888
Diclofenac is a preferential cyclooxygenase 2 inhibitor (COX-2) and member of non-steroidal anti-inflammatory drugs (NSAIDs). Inflammation is one of the main reason of poor prognosis of colon cancer cases; thereby...
9.
Ozfiliz-Kilbas P, Sarikaya B, Obakan-Yerlikaya P, Coker-Gurkan A, Arisan E, Temizci B, et al.
Mol Biol Rep
. 2018 Jul;
45(5):815-828.
PMID: 29978381
Roscovitine (Rosc) and purvalanol (Pur) are competitive inhibitors of cyclin-dependent kinases (CDKs) by targeting their ATP-binding pockets. Both drugs are shown to be effective to decrease cell viability and dysregulate...
10.
Coker-Gurkan A, Celik M, Ugur M, Arisan E, Obakan-Yerlikaya P, Durdu Z, et al.
Amino Acids
. 2018 May;
50(8):1045-1069.
PMID: 29770869
Curcumin is assumed to be a plant-derived therapeutic drug that triggers apoptotic cell death in vitro and in vivo by affecting different molecular targets such as NF-κB. Phase I/II trial...