Pim W van der Helm
Overview
Explore the profile of Pim W van der Helm including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
4
Citations
101
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Lin C, Levy P, Alflen A, Apriamashvili G, Ligtenberg M, Vredevoogd D, et al.
Cancer Cell
. 2024 Mar;
42(4):623-645.e10.
PMID: 38490212
Genes limiting T cell antitumor activity may serve as therapeutic targets. It has not been systematically studied whether there are regulators that uniquely or broadly contribute to T cell fitness....
2.
van de Haar J, Ma X, Ooft S, van der Helm P, Hoes L, Mainardi S, et al.
Nat Med
. 2023 Mar;
29(3):605-614.
PMID: 36864254
Genomics has greatly improved how patients with cancer are being treated; however, clinical-grade genomic biomarkers for chemotherapies are currently lacking. Using whole-genome analysis of 37 patients with metastatic colorectal cancer...
3.
Zhang Z, Kong X, Ligtenberg M, van Hal-van Veen S, Visser N, de Bruijn B, et al.
Cell Rep Med
. 2022 Jun;
3(6):100655.
PMID: 35688159
Tumor escape mechanisms for immunotherapy include deficiencies in antigen presentation, diminishing adaptive CD8 T cell antitumor activity. Although innate natural killer (NK) cells are triggered by loss of MHC class...
4.
Condon K, Orozco J, Adelmann C, Spinelli J, van der Helm P, Roberts J, et al.
Proc Natl Acad Sci U S A
. 2021 Jan;
118(4).
PMID: 33483422
In mammalian cells, nutrients and growth factors signal through an array of upstream proteins to regulate the mTORC1 growth control pathway. Because the full complement of these proteins has not...