Pim W Gilijamse
Overview
Explore the profile of Pim W Gilijamse including associated specialties, affiliations and a list of published articles.
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9
Citations
373
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Recent Articles
1.
Yildirim V, Ter Horst K, Gilijamse P, van Harskamp D, Schierbeek H, Jansen H, et al.
JCI Insight
. 2023 Jul;
8(16).
PMID: 37432744
Dyslipidemia in obesity results from excessive production and impaired clearance of triglyceride-rich (TG-rich) lipoproteins, which are particularly pronounced in the postprandial state. Here, we investigated the impact of Roux-en-Y gastric...
2.
Gilijamse P, Demirkiran A, van Wagensveld B, Ackermans M, Romijn J, Nieuwdorp M, et al.
Surg Obes Relat Dis
. 2021 Jun;
17(8):1440-1448.
PMID: 34083134
Background: Glucagon-like peptide-1 (GLP-1) receptor agonist treatment is beneficial for the human glucose metabolism, and GLP-1 secretion is greatly enhanced following Roux-en-Y gastric bypass (RYGB). Objectives: To elucidate the relationship...
3.
Gilijamse P, Hartstra A, Levin E, Wortelboer K, Serlie M, Ackermans M, et al.
NPJ Biofilms Microbiomes
. 2020 Mar;
6(1):16.
PMID: 32221294
Dysbiosis of the intestinal microbiota has been implicated in insulin resistance, although evidence regarding causality in humans is scarce. We performed a phase I/II dose-finding and safety study on the...
4.
The pathophysiology of human obstructive cholestasis is mimicked in cholestatic Gold Syrian hamsters
van Golen R, Olthof P, de Haan L, Coelen R, Pechlivanis A, de Keijzer M, et al.
Biochim Biophys Acta Mol Basis Dis
. 2017 Dec;
1864(3):942-951.
PMID: 29196240
Obstructive cholestasis causes liver injury via accumulation of toxic bile acids (BAs). Therapeutic options for cholestatic liver disease are limited, partially because the available murine disease models lack translational value....
5.
Ter Horst K, Gilijamse P, Demirkiran A, van Wagensveld B, Ackermans M, Verheij J, et al.
Mol Metab
. 2017 Nov;
6(11):1493-1502.
PMID: 29107295
Objective: Fructose consumption has been implicated in the development of obesity and insulin resistance. Emerging evidence shows that fibroblast growth factor 21 (FGF21) has beneficial effects on glucose, lipid, and...
6.
Ter Horst K, Gilijamse P, Versteeg R, Ackermans M, Nederveen A, la Fleur S, et al.
Cell Rep
. 2017 Jun;
19(10):1997-2004.
PMID: 28591572
Hepatic lipid accumulation has been implicated in the development of insulin resistance, but translational evidence in humans is limited. We investigated the relationship between liver fat and tissue-specific insulin sensitivity...
7.
Ter Horst K, Gilijamse P, Ackermans M, Soeters M, Nieuwdorp M, Romijn J, et al.
Metabolism
. 2016 Apr;
65(5):757-763.
PMID: 27085782
Aim: Elevated basal endogenous glucose production (EGP), impaired suppression of EGP by insulin and reduced insulin-stimulated glucose disposal are cornerstones of the pathogenesis of hyperglycemia in patients with type 2...
8.
Ter Horst K, Gilijamse P, de Weijer B, Kilicarslan M, Ackermans M, Nederveen A, et al.
Front Endocrinol (Lausanne)
. 2015 Dec;
6:182.
PMID: 26635731
Glucose and lipid metabolism differ between men and women, and women tend to have better whole-body or muscle insulin sensitivity. This may be explained, in part, by differences in sex...
9.
Nieuwdorp M, Gilijamse P, Pai N, Kaplan L
Gastroenterology
. 2014 Feb;
146(6):1525-33.
PMID: 24560870
Intestinal microbes regulate metabolic function and energy balance; an altered microbial ecology is believed to contribute to the development of several metabolic diseases. Relative species abundance and metabolic characteristics of...