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Pilar Horcajo

Explore the profile of Pilar Horcajo including associated specialties, affiliations and a list of published articles. Areas
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Articles 46
Citations 306
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Recent Articles
1.
Collantes-Fernandez E, Horcajo P, Benavides J, Sanchez-Sanchez R, Blanco-Murcia J, Montaner-Da Torre S, et al.
Theriogenology . 2024 Oct; 230:305-313. PMID: 39368452
Bovine abortions, often caused by infectious agents like Neospora caninum, inflict substantial economic losses. Studying host-pathogen interactions in pregnant cows is challenging, and existing cell cultures lack the intricate complexity...
2.
Rico-San Roman L, Hanggeli K, Hemphill A, Horcajo P, Collantes-Fernandez E, Ortega-Mora L, et al.
Front Cell Infect Microbiol . 2024 Jul; 14:1419209. PMID: 38975328
As for many other organisms, CRISPR-Cas9 mediated genetic modification has gained increasing importance for the identification of vaccine candidates and drug targets in , an apicomplexan parasite causing abortion in...
3.
Fernandez-Alvarez M, Horcajo P, Jimenez-Melendez A, Lara P, Huertas-Lopez A, Huertas-Lopez F, et al.
Microorganisms . 2024 Mar; 12(3). PMID: 38543637
Endothelial injury, inflammatory infiltrate and fibrosis are the predominant lesions in the testis of bulls with besnoitiosis that may result in sterility. Moreover, fibroblasts, which are key players in fibrosis,...
4.
Hecker Y, Gonzalez-Ortega S, Cano S, Ortega-Mora L, Horcajo P
Front Vet Sci . 2023 Oct; 10:1249410. PMID: 37841464
The aim of the present systematic review and meta-analysis was to identify the main infectious agents related to bovine abortion worldwide in the period between 2000 and 2022. First, we...
5.
Horcajo P, Ortega-Mora L, Benavides J, Sanchez-Sanchez R, Amieva R, Collantes-Fernandez E, et al.
Theriogenology . 2023 Sep; 212:157-171. PMID: 37729817
Reproductive failure is one of the main performance constraints in ruminant livestock. Transmissible agents such as Toxoplasma gondii and Neospora caninum are commonly involved in the occurrence of abortion in...
6.
Horcajo P, Coronado M, Pastor-Fernandez I, Collantes-Fernandez E, Rico-San Roman L, Reyes-Palomares A, et al.
Front Immunol . 2023 Jul; 14:1198609. PMID: 37520552
Research on bovine neosporosis has achieved relevant milestones, but the mechanisms underlying the occurrence of foetal death or protection against foetal death remain unclear. In a recent study, placentas from...
7.
Rico-San Roman L, Amieva R, Horcajo P, Garcia-Sanchez M, Pastor-Fernandez I, Ortega-Mora L, et al.
Vet Parasitol . 2023 Jun; 320:109973. PMID: 37356132
Bovine neosporosis is one of the major causes of reproductive failure in cattle worldwide, and differences in virulence between isolates have been widely shown. However, the molecular basis and mechanisms...
8.
Fernandez-Alvarez M, Horcajo P, Jimenez-Melendez A, Diezma-Diaz C, Ferre I, Pastor-Fernandez I, et al.
Int J Parasitol . 2023 May; 53(9):505-521. PMID: 37207972
Besnoitia besnoiti-infected bulls may develop severe systemic clinical signs and orchitis that may ultimately cause sterility during the acute infection. Macrophages might play a relevant role in pathogenesis of the...
9.
Rico-San Roman L, Amieva R, Regidor-Cerrillo J, Garcia-Sanchez M, Collantes-Fernandez E, Pastor-Fernandez I, et al.
Pathogens . 2022 Sep; 11(9). PMID: 36145430
The intraspecific variability among isolates in their in vitro behaviour and in vivo virulence has been widely studied. In particular, transcriptomic and proteomic analyses have shown a higher expression/abundance of...
10.
Mas A, Martinez-Rodrigo A, Carrion J, Orden J, Alzate J, Dominguez-Bernal G, et al.
Int J Mol Sci . 2022 Feb; 23(3). PMID: 35163386
Zoonotic visceral leishmaniosis caused by is an endemic disease in the Mediterranean Basin affecting mainly humans and dogs, the main reservoir. The leishmaniosis outbreak declared in the Community of Madrid...