Pieter Coussement
Overview
Explore the profile of Pieter Coussement including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
160
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0
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Recent Articles
1.
Goormans A, Snoeck N, Decadt H, Vermeulen K, Peters G, Coussement P, et al.
Metab Eng
. 2020 Aug;
62:10-19.
PMID: 32795614
As a biorefinery platform host, Escherichia coli has been used extensively to produce metabolites of commercial interest. Integration of foreign DNA onto the bacterial genome allows for stable expression overcoming...
2.
Lodens S, Roelants S, Luyten G, Geys R, Coussement P, De Maeseneire S, et al.
FEMS Yeast Res
. 2020 Apr;
20(3).
PMID: 32329773
Starmerella bombicola very efficiently produces the secondary metabolites sophorolipids (SLs). Their biosynthesis is not-growth associated and highly upregulated in the stationary phase. Despite high industrial and academic interest, the underlying...
3.
Coussement P, Bauwens D, Peters G, Maertens J, De Mey M
Biotechnol Adv
. 2020 Jan;
40:107512.
PMID: 31953205
Microorganisms possess a plethora of regulatory mechanisms to tightly control the flux through their metabolic network, allowing optimal behaviour in response to environmental conditions. However, these mechanisms typically counteract metabolic...
4.
Snoeck N, De Mol M, Van Herpe D, Goormans A, Maryns I, Coussement P, et al.
Biotechnol Bioeng
. 2018 Oct;
116(2):364-374.
PMID: 30345503
Chromosomal integration of biosynthetic pathways for the biotechnological production of high-value chemicals is a necessity to develop industrial strains with a high long-term stability and a low production variability. However,...
5.
Decoene T, De Paepe B, Maertens J, Coussement P, Peters G, De Maeseneire S, et al.
Crit Rev Biotechnol
. 2017 Sep;
38(5):647-656.
PMID: 28954542
Background: Leaping DNA read-and-write technologies, and extensive automation and miniaturization are radically transforming the field of biological experimentation by providing the tools that enable the cost-effective high-throughput required to address...
6.
De Paepe B, Peters G, Coussement P, Maertens J, De Mey M
J Ind Microbiol Biotechnol
. 2016 Nov;
44(4-5):623-645.
PMID: 27837353
Monitoring cellular behavior and eventually properly adapting cellular processes is key to handle the enormous complexity of today's metabolic engineering questions. Hence, transcriptional biosensors bear the potential to augment and...
7.
Coussement P, Bauwens D, Maertens J, De Mey M
ACS Synth Biol
. 2016 Sep;
6(2):224-232.
PMID: 27672702
Combinatorial engineering approaches are becoming increasingly popular, yet they are hindered by the lack of specialized techniques for both efficient introduction of sequence variability and assembly of numerous DNA parts,...
8.
Peters G, Coussement P, Maertens J, Lammertyn J, De Mey M
Biotechnol Adv
. 2015 Oct;
33(8):1829-44.
PMID: 26514597
Synthetic biology, in close concert with systems biology, is revolutionizing the field of metabolic engineering by providing novel tools and technologies to rationally, in a standardized way, reroute metabolism with...
9.
Coussement P, Maertens J, Beauprez J, Van Bellegem W, De Mey M
Metab Eng
. 2014 Mar;
23:70-7.
PMID: 24594279
The rapid and efficient assembly of multi-step metabolic pathways for generating microbial strains with desirable phenotypes is a critical procedure for metabolic engineering, and remains a significant challenge in synthetic...