Pieter Bas Kwak
Overview
Explore the profile of Pieter Bas Kwak including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
513
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0
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Recent Articles
1.
Gillessen M, Kwak P, Tamayo A
F1000Res
. 2017 Sep;
6:1316.
PMID: 28928952
The proteins CLOCK and BMAL1 form a heterodimeric transcription factor essential to circadian rhythms in mammals. Daily rhythms of CLOCK-BMAL1 DNA binding activity are known to oscillate with target gene...
2.
Aryal R, Kwak P, Tamayo A, Gebert M, Chiu P, Walz T, et al.
Mol Cell
. 2017 Sep;
67(5):770-782.e6.
PMID: 28886335
The mammalian circadian clock is built on a feedback loop in which PER and CRY proteins repress their own transcription. We found that in mouse liver nuclei all three PERs,...
3.
Kim J, Kwak P, Gebert M, Duong H, Weitz C
Methods Enzymol
. 2015 Feb;
551:197-210.
PMID: 25662458
In mammals, circadian rhythms are generated at least in part by a cell-autonomous transcriptional feedback loop in which the three PERIOD (PER) and two CRYPTOCHROME (CRY) proteins inhibit the activity...
4.
Kim J, Kwak P, Weitz C
Mol Cell
. 2014 Dec;
56(6):738-48.
PMID: 25453762
Mammalian circadian rhythms are generated by a negative feedback loop in which PERIOD (PER) proteins accumulate, form a large nuclear complex (PER complex), and bind the transcription factor CLOCK-BMAL1, repressing...
5.
Kwak P, Tomari Y
Nat Struct Mol Biol
. 2012 Jan;
19(2):145-51.
PMID: 22233755
Small RNAs, such as microRNAs and small interfering RNAs, act through Argonaute (Ago) proteins as a part of RNA-induced silencing complexes (RISCs). To make RISCs, Ago proteins bind and subsequently...
6.
Kwak P, Iwasaki S, Tomari Y
Cancer Sci
. 2010 Aug;
101(11):2309-15.
PMID: 20726859
MicroRNAs (miRNAs) are ∼22nt long, non-coding RNAs that guide post-transcriptional gene silencing of their target genes and regulate diverse biological processes including cancer. miRNAs do not act alone, but require...
7.
Kwak P, Wang Q, Chen X, Qiu C, Yang Z
BMC Genomics
. 2009 Oct;
10:457.
PMID: 19788742
Background: Cotton (Gossypium hirsutum) is one of the most important economic crops and provides excellent fibers for textile manufacture. In addition to its industrial and agricultural importance, the fiber cell...