Pierre Formstecher
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Explore the profile of Pierre Formstecher including associated specialties, affiliations and a list of published articles.
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44
Citations
1081
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Recent Articles
11.
Touil Y, Zuliani T, Wolowczuk I, Kuranda K, Prochazkova J, Andrieux J, et al.
Stem Cells
. 2013 Jan;
31(4):641-51.
PMID: 23355370
Melanoma is one of the most aggressive and extremely resistant to conventional therapies neoplasms. Recently, cellular resistance was linked to the cancer stem cell phenotype, still controversial and not well-defined....
12.
Kluza J, Corazao-Rozas P, Touil Y, Jendoubi M, Maire C, Guerreschi P, et al.
Cancer Res
. 2012 Aug;
72(19):5035-47.
PMID: 22865452
Cancer cells can undergo a metabolic reprogramming from oxidative phosphorylation to glycolysis that allows them to adapt to nutrient-poor microenvironments, thereby imposing a selection for aggressive variants. However, the mechanisms...
13.
Ballot C, Jendoubi M, Kluza J, Jonneaux A, Laine W, Formstecher P, et al.
Apoptosis
. 2011 Dec;
17(4):364-76.
PMID: 22127645
F14512, an epipodophyllotoxin derivative equipped with a spermine moiety, is selectively taken up by the polyamine transport system over-active in tumor cells. F14512 was identified as a selective anticancer agent...
14.
Kluza J, Jendoubi M, Ballot C, Dammak A, Jonneaux A, Idziorek T, et al.
PLoS One
. 2011 Jul;
6(7):e21924.
PMID: 21789194
Challenges today concern chronic myeloid leukemia (CML) patients resistant to imatinib. There is growing evidence that imatinib-resistant leukemic cells present abnormal glucose metabolism but the impact on mitochondria has been...
15.
Dezitter X, Masselot B, Tardivel M, Mereau-Richard C, Formstecher P, Idziorek T
J Steroid Biochem Mol Biol
. 2011 May;
126(3-5):104-12.
PMID: 21569845
The ability of inhibitors of transcription and translation to prevent glucocorticoid-induced apoptosis has been interpreted to indicate that the cell death machinery requires de novo protein synthesis. The transcriptional inhibitors...
16.
Mortier L, Delesalle F, Formstecher P, Polakowska R
Exp Dermatol
. 2010 Sep;
19(10):929-30.
PMID: 20849536
Recently, human embryonic stem cells have been differentiated in vitro into functional epidermal keratinocytes. Here, we demonstrated that these cells can be generated also from non-embryonic, human umbilical cord blood...
17.
Ballot C, Kluza J, Lancel S, Martoriati A, Hassoun S, Mortier L, et al.
Apoptosis
. 2010 Feb;
15(7):769-81.
PMID: 20151196
Lamellarin D (Lam D), a marine alkaloid, exhibits a potent cytotoxicity against many different tumors. The pro-apoptotic function of Lam D has been attributed to its direct induction of mitochondrial...
18.
Ballot C, Kluza J, Martoriati A, Nyman U, Formstecher P, Joseph B, et al.
Mol Cancer Ther
. 2009 Dec;
8(12):3307-17.
PMID: 19952118
Lamellarin D, a potent cytotoxic marine alkaloid, exerts its antitumor action through two complementary pathways: a nuclear route via topoisomerase I inhibition and a mitochondrial targeting. The present study was...
19.
Le Roy H, Zuliani T, Wolowczuk I, Faivre N, Jouy N, Masselot B, et al.
Stem Cells Dev
. 2009 Oct;
19(2):209-20.
PMID: 19799519
Cancer cells are unequal in a tumor mass and in established cultures. This is attributable to cancer stem cells with the unique ability to self-renew and to generate differentiating progeny....
20.
Castera L, Hatzfeld-Charbonnier A, Ballot C, Charbonnel F, Dhuiege E, Velu T, et al.
J Cell Mol Med
. 2008 May;
13(7):1321-35.
PMID: 18466357
The death of dendritic cells (DCs) can potentially influence immune responses by affecting the duration of DC stimulation of lymphocytes. Here, we report that cultured mature monocyte-derived DCs manifest early...