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Pierre Bongrand

Explore the profile of Pierre Bongrand including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 1203
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Recent Articles
1.
Bongrand P
Int J Mol Sci . 2025 Jan; 25(24. PMID: 39769135
During the last decade, artificial intelligence (AI) was applied to nearly all domains of human activity, including scientific research. It is thus warranted to ask whether AI thinking should be...
2.
Bertin D, Bongrand P, Bardin N
Int J Mol Sci . 2024 Mar; 25(6). PMID: 38542244
The success of artificial intelligence and machine learning is an incentive to develop new algorithms to increase the rapidity and reliability of medical diagnosis. Here we compared different strategies aimed...
3.
Bongrand P
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768586
Cell biologists have long aimed at quantitatively modeling cell function. Recently, the outstanding progress of high-throughput measurement methods and data processing tools has made this a realistic goal. The aim...
4.
Bongrand P
Curr Issues Mol Biol . 2022 Jun; 44(2):505-525. PMID: 35723321
An important goal of biological research is to explain and hopefully predict cell behavior from the molecular properties of cellular components. Accordingly, much work was done to build extensive "omic"...
5.
Puech P, Bongrand P
Open Biol . 2021 Nov; 11(11):210256. PMID: 34753321
How do cells process environmental cues to make decisions? This simple question is still generating much experimental and theoretical work, at the border of physics, chemistry and biology, with strong...
6.
Robert P, Limozin L, Anton van der Merwe P, Bongrand P
Cells . 2021 Mar; 10(2). PMID: 33670573
The scanning of surrounding tissues by T lymphocytes to detect cognate antigens requires high speed, sensitivity and specificity. T-cell receptor (TCR) co-receptors such as CD8 increase detection performance, but the...
7.
Limozin L, Bridge M, Bongrand P, Dushek O, van der Merwe P, Robert P
Proc Natl Acad Sci U S A . 2019 Jul; 116(34):16943-16948. PMID: 31315981
The T cell receptor (TCR)-peptide-MHC (pMHC) interaction is the only antigen-specific interaction during T lymphocyte activation. Recent work suggests that formation of catch bonds is characteristic of activating TCR-pMHC interactions....
8.
Limozin L, Bongrand P, Robert P
Sci Rep . 2016 Oct; 6:35193. PMID: 27731375
Antibodies and B cell receptors often bind their antigen at cell-cell interface while both molecular species are surface-bound, which impacts bond kinetics and function. Despite the description of complex energy...
9.
Preira P, Forel J, Robert P, Negre P, Biarnes-Pelicot M, Xeridat F, et al.
Crit Care . 2016 Jan; 20:8. PMID: 26757701
Background: Leukocyte-mediated pulmonary inflammation is a key pathophysiological mechanism involved in acute respiratory distress syndrome (ARDS). Massive sequestration of leukocytes in the pulmonary microvasculature is a major triggering event of...
10.
Bertin D, Mouhajir Y, Bongrand P, Bardin N
Clin Chim Acta . 2016 Jan; 454:57-61. PMID: 26742604
Background: Antinuclear antibodies (ANA) are useful biomarkers for the diagnosis and the monitoring of rheumatic diseases. The American College of Rheumatology has stated that indirect immunofluorescence (IIF) analysis remains the...