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Pierre-Antoine Dugue

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Articles 101
Citations 1803
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Recent Articles
1.
Onwuka J, Guida F, Langdon R, Johansson M, Severi G, Milne R, et al.
BMJ Oncol . 2025 Jan; 3(1):e000334. PMID: 39886123
Objective: Screening high-risk individuals with low-dose CT reduces mortality from lung cancer, but many lung cancers occur in individuals who are not eligible for screening. Risk biomarkers may be useful...
2.
Zarean E, Li S, Wong E, Makalic E, Milne R, Giles G, et al.
Breast Cancer Res . 2025 Jan; 27(1):9. PMID: 39825380
Background: Tumour DNA methylation has been investigated as a potential marker for breast cancer survival, but findings often lack replication across studies. Methods: This study sought to replicate previously reported...
3.
Zarean E, Li S, Wong E, Makalic E, Milne R, Giles G, et al.
Epigenomics . 2024 Dec; 17(2):105-114. PMID: 39711216
Aims: Clustering algorithms have been widely applied to tumor DNA methylation datasets to define methylation-based cancer subtypes. This study aimed to evaluate the agreement between subtypes obtained from common clustering...
4.
Hosseinpour M, Xi X, Liu L, Malaver-Ortega L, Perlaza-Jimenez L, Joo J, et al.
Nat Commun . 2024 Dec; 15(1):10449. PMID: 39617792
DNA methylation is an epigenetic mark that plays a critical role in regulating gene expression. DNA methyltransferase (DNMT) inhibitors, inhibit global DNA methylation and have been a key tool in...
5.
Wu Y, Xu R, Li S, Wen B, Southey M, Dugue P, et al.
J Hazard Mater . 2024 Nov; 481():136486. PMID: 39566450
Wildfire-related PM has been associated with various adverse health outcomes, but its association with epigenetic aging remains unclear. This study examined the association between wildfire-related PM exposure and epigenetic aging...
6.
McLennan E, Li D, Southey M, Dugue P
Cancer Med . 2024 Nov; 13(21):e70355. PMID: 39529385
Background: Age is one of the strongest risk factors for breast cancer. Measures of biological age based on DNA methylation have gained popularity for their strong association with risk of...
7.
Zheng H, Li D, Lou M, Hodge A, Southey M, Giles G, et al.
Geroscience . 2024 Nov; PMID: 39508977
Epigenetic age quantifies biological age using DNA methylation information and is a potential pathway by which physical activity benefits general health. We aimed to assess the cross-sectional and longitudinal associations...
8.
Alpen K, Maclnnis R, Vajdic C, Lai J, Dowty J, Koh E, et al.
Cancer Res Commun . 2024 Oct; 4(11):2933-2946. PMID: 39387520
Further investigation of the potential susceptibility regions identified in our study may lead to a better understanding of glioma genetic risk and the underlying biological etiology of glioma. Our study...
9.
Cribb L, Hodge A, Southey M, Giles G, Milne R, Dugue P
Geroscience . 2024 Sep; PMID: 39298107
The role of nutrition in healthy ageing is acknowledged but details of optimal dietary composition are still uncertain. We aimed to investigate the cross-sectional associations between dietary exposures, including macronutrient...
10.
Zheng H, Lou M, Dugue P, Lynch B
Cancer Epidemiol . 2024 Sep; 93:102662. PMID: 39243578
Evidence suggests that inflammation may be associated with a higher risk of endometrial cancer, but previous reviews have typically examined a limited number of biomarkers. This study aimed to critically...