Pierre-Alexis Gros
Overview
Explore the profile of Pierre-Alexis Gros including associated specialties, affiliations and a list of published articles.
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5
Citations
212
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Recent Articles
1.
Bonnaffoux A, Herbach U, Richard A, Guillemin A, Gonin-Giraud S, Gros P, et al.
BMC Bioinformatics
. 2019 May;
20(1):220.
PMID: 31046682
Background: Inference of gene regulatory networks from gene expression data has been a long-standing and notoriously difficult task in systems biology. Recently, single-cell transcriptomic data have been massively used for...
2.
Jacquier H, Birgy A, Le Nagard H, Mechulam Y, Schmitt E, Glodt J, et al.
Proc Natl Acad Sci U S A
. 2013 Jul;
110(32):13067-72.
PMID: 23878237
Adaptation proceeds through the selection of mutations. The distribution of mutant fitness effect and the forces shaping this distribution are therefore keys to predict the evolutionary fate of organisms and...
3.
Bleibtreu A, Gros P, Laouenan C, Clermont O, Le Nagard H, Picard B, et al.
Infect Immun
. 2013 May;
81(8):2733-42.
PMID: 23690401
The extraintestinal virulence of Escherichia coli is dependent on numerous virulence genes. However, there is growing evidence for a role of the metabolic properties and stress responses of strains in...
4.
Gros P, Tenaillon O
Genetics
. 2009 Mar;
182(2):555-64.
PMID: 19307609
Genetic robustness is defined as the constancy of a phenotype in the face of deleterious mutations. Overexpression of chaperones, to assist the folding of proteins carrying deleterious mutations, is so...
5.
Gros P, Le Nagard H, Tenaillon O
Genetics
. 2009 Mar;
182(1):277-93.
PMID: 19279327
The epistatic interactions among mutations have a large effect on the evolution of populations. In this article we provide a formalism under which epistatic interactions among pairs of mutations have...