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Pierre-Alexandre Vidi

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Articles 44
Citations 1197
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Recent Articles
1.
Gaber M, Quentel A, Holmes J, Lepetit C, Triki H, Wilson A, et al.
Breast Cancer Res . 2025 Jan; 27(1):11. PMID: 39838489
Obesity is a modifiable risk factor for breast cancer. Yet, how obesity contributes to cancer initiation is not fully understood. The goal of this study was to determine if the...
2.
Coquelet H, Leman G, Maarouf A, Petit C, Toutain B, Henry C, et al.
FEBS J . 2025 Jan; PMID: 39756023
Senescence is a tumor suppressor mechanism triggered by oncogene expression and chemotherapy treatment. It orchestrates a definitive cessation of cell proliferation through the activation of the p53-p21 and p16-Rb pathways,...
3.
Vidi P, Liu J, Bonin K, Bloom K
Nucleus . 2024 Dec; 16(1):2438633. PMID: 39720924
Chromatin is a dynamic polymer in constant motion. These motions are heterogeneous between cells and within individual cell nuclei and are profoundly altered in response to DNA damage. The shifts...
4.
Swavey S, Quentel A, Grzesiak M, Hawkins C, Vidi P
RSC Adv . 2024 Dec; 14(52):38796-38805. PMID: 39654916
Generation of reactive oxygen species (ROS) within the ER evokes stress leading to immunogenic cell death. A red light activated BODIPY dye capable of subcellular localization within the ER producing...
5.
Maarouf A, Iqbal F, Sanaullah S, Locatelli M, Atanasiu A, Kolbin D, et al.
Mol Biol Cell . 2024 Sep; 35(11):ar136. PMID: 39292916
In yeasts and higher eukaryotes, chromatin motions may be tuned to genomic functions, with transcriptional activation and the DNA damage response both leading to profound changes in chromatin dynamics. The...
6.
Lepetit C, Gaber M, Zhou K, Chen H, Holmes J, Summers P, et al.
Expo Health . 2024 Sep; 16(4):1039-1052. PMID: 39220725
Supplementary Information: The online version contains supplementary material available at 10.1007/s12403-023-00609-1.
7.
Holmes J, Gaber M, Jenks M, Wilson A, Loy T, Lepetit C, et al.
NPJ Breast Cancer . 2023 May; 9(1):35. PMID: 37160903
Molecular links between breast cancer risk factors and pro-oncogenic tissue alterations are poorly understood. The goal of this study was to characterize the impact of overweight and obesity on tissue...
8.
Bonin K, Prasad S, Caulkins W, Holzwarth G, Baker S, Vidi P
J Biomed Opt . 2023 Jan; 27(12):126501. PMID: 36590978
Significance: Three-dimensional (3D) imaging and object tracking is critical for medical and biological research and can be achieved by multifocal imaging with diffractive optical elements (DOEs) converting depth ( )...
9.
Locatelli M, Lawrimore J, Lin H, Sanaullah S, Seitz C, Segall D, et al.
Proc Natl Acad Sci U S A . 2022 Jul; 119(29):e2205166119. PMID: 35858349
Chromatin motions depend on and may regulate genome functions, in particular the DNA damage response. In yeast, DNA double-strand breaks (DSBs) globally increase chromatin diffusion, whereas in higher eukaryotes the...
10.
Prajapati S, Locatelli M, Sawyer C, Holmes J, Bonin K, Black P, et al.
Mutat Res . 2021 Dec; 824:111772. PMID: 34923215
The study of radiation effects on biological tissues is a diverse field of research with direct applications to improve human health, in particular in the contexts of radiation therapy and...