Piero Pingitore
Overview
Explore the profile of Piero Pingitore including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
1235
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0
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Recent Articles
1.
Mancina R, Sasidharan K, Lindblom A, Wei Y, Ciociola E, Jamialahmadi O, et al.
Nat Metab
. 2022 Feb;
4(1):60-75.
PMID: 35102341
Fatty liver disease (FLD) is a growing health issue with burdening unmet clinical needs. FLD has a genetic component but, despite the common variants already identified, there is still a...
2.
Caddeo A, Hedfalk K, Romeo S, Pingitore P
Biochim Biophys Acta Mol Cell Biol Lipids
. 2021 Jan;
1866(5):158891.
PMID: 33513444
Human membrane bound O-acyltransferase domain-containing 7 (MBOAT7), also known as lysophosphatidylinositol acyltransferase 1 (LPIAT1), is an enzyme involved in the acyl-chain remodeling of phospholipids via the Lands' cycle. The MBOAT7...
3.
Schwartz B, Rajagopal V, Smith C, Cohick E, Whissell G, Gamboa M, et al.
Cells
. 2020 Oct;
9(10).
PMID: 33036387
Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are emerging worldwide epidemics, projected to become the leading cause of liver transplants. The strongest genetic risk factor for NAFLD/NASH susceptibility...
4.
Baselli G, Dongiovanni P, Rametta R, Meroni M, Pelusi S, Maggioni M, et al.
Gut
. 2020 Feb;
69(10):1855-1866.
PMID: 32001554
Objective: Efforts to manage non-alcoholic fatty liver disease (NAFLD) are limited by the incomplete understanding of the pathogenic mechanisms and the absence of accurate non-invasive biomarkers. The aim of this...
5.
Prill S, Caddeo A, Baselli G, Jamialahmadi O, Dongiovanni P, Rametta R, et al.
Sci Rep
. 2019 Aug;
9(1):11585.
PMID: 31406127
There is a high unmet need for developing treatments for nonalcoholic fatty liver disease (NAFLD), for which there are no approved drugs today. Here, we used a human in vitro...
6.
Pingitore P, Sasidharan K, Ekstrand M, Prill S, Linden D, Romeo S
Int J Mol Sci
. 2019 Apr;
20(7).
PMID: 30986904
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disorder in western countries. Despite the high prevalence of NAFLD, the underlying biology of the disease progression is not clear,...
7.
Caddeo A, Jamialahmadi O, Solinas G, Pujia A, Mancina R, Pingitore P, et al.
J Struct Biol
. 2019 Apr;
206(3):349-360.
PMID: 30959108
Membrane bound O-acyltransferase domain- containing 7 (MBOAT7, also known as LPIAT1) is a protein involved in the acyl chain remodeling of phospholipids via the Lands' cycle. The MBOAT7 is a...
8.
Linden D, Ahnmark A, Pingitore P, Ciociola E, Ahlstedt I, Andreasson A, et al.
Mol Metab
. 2019 Feb;
22:49-61.
PMID: 30772256
Objective: Nonalcoholic fatty liver disease (NAFLD) is becoming a leading cause of advanced chronic liver disease. The progression of NAFLD, including nonalcoholic steatohepatitis (NASH), has a strong genetic component, and...
9.
Botta M, Maurer E, Ruscica M, Romeo S, Stulnig T, Pingitore P
Atherosclerosis
. 2019 Jan;
282:45-51.
PMID: 30685441
Background And Aims: Type I hyperlipoproteinemia is an autosomal recessive disorder of lipoprotein metabolism caused by mutations in the LPL gene, with an estimated prevalence in the general population of...
10.
Pingitore P, Romeo S
Biochim Biophys Acta Mol Cell Biol Lipids
. 2018 Jun;
1864(6):900-906.
PMID: 29935383
The human patatin-like phospholipase domain-containing 3 (PNPLA3) gene encodes for a protein of 481 amino-acids. The variant rs738409 is a cytosine to guanine substitution, encoding for the isoleucine to methionine...