Phillip L Lowrey
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Explore the profile of Phillip L Lowrey including associated specialties, affiliations and a list of published articles.
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7
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2053
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Recent Articles
1.
Maniscalco M, Nannen J, Sodi V, Silver G, Lowrey P, Bidle K
Front Microbiol
. 2014 Mar;
5:79.
PMID: 24624125
Circadian rhythms are important biological signals that have been found in almost all major groups of life from bacteria to man, yet it remains unclear if any members of the...
2.
Shimomura K, Kumar V, Koike N, Kim T, Chong J, Buhr E, et al.
Elife
. 2013 Apr;
2:e00426.
PMID: 23580255
Genetic and molecular approaches have been critical for elucidating the mechanism of the mammalian circadian clock. Here, we demonstrate that the ClockΔ19 mutant behavioral phenotype is significantly modified by mouse...
3.
Lowrey P, Takahashi J
Adv Genet
. 2011 Sep;
74:175-230.
PMID: 21924978
The mammalian circadian system is a complex hierarchical temporal network which is organized around an ensemble of uniquely coupled cells comprising the principal circadian pacemaker in the suprachiasmatic nucleus of...
4.
Shimomura K, Lowrey P, Vitaterna M, Buhr E, Kumar V, Hanna P, et al.
Proc Natl Acad Sci U S A
. 2010 Apr;
107(18):8399-403.
PMID: 20404168
Most laboratory mouse strains including C57BL/6J do not produce detectable levels of pineal melatonin owing to deficits in enzymatic activity of arylalkylamine N-acetyltransferase (AANAT) and N-acetylserotonin O-methyl transferase (ASMT), two...
5.
Yoo S, Ko C, Lowrey P, Buhr E, Song E, Chang S, et al.
Proc Natl Acad Sci U S A
. 2005 Feb;
102(7):2608-13.
PMID: 15699353
The mouse Period2 (mPer2) locus is an essential negative-feedback element of the mammalian circadian-clock mechanism. Recent work has shown that mPer2 circadian gene expression persists in both central and peripheral...
6.
Lowrey P, Takahashi J
Annu Rev Genomics Hum Genet
. 2004 Oct;
5:407-41.
PMID: 15485355
During the past decade, the molecular mechanisms underlying the mammalian circadian clock have been defined. A core set of circadian clock genes common to most cells throughout the body code...
7.
Yoo S, Yamazaki S, Lowrey P, Shimomura K, Ko C, Buhr E, et al.
Proc Natl Acad Sci U S A
. 2004 Feb;
101(15):5339-46.
PMID: 14963227
Mammalian circadian rhythms are regulated by the suprachiasmatic nucleus (SCN), and current dogma holds that the SCN is required for the expression of circadian rhythms in peripheral tissues. Using a...