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Philippe Mazodier

Explore the profile of Philippe Mazodier including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 168
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Recent Articles
1.
Boubakri H, Seghezzi N, Duchateau M, Gominet M, Kofronova O, Benada O, et al.
J Bacteriol . 2015 Aug; 197(21):3388-99. PMID: 26283768
Unlabelled: Protein turnover is essential in all living organisms for the maintenance of normal cell physiology. In eukaryotes, most cellular protein turnover involves the ubiquitin-proteasome pathway, in which proteins tagged...
2.
Guyet A, Benaroudj N, Proux C, Gominet M, Coppee J, Mazodier P
BMC Microbiol . 2014 Apr; 14:81. PMID: 24694298
Background: AdpA is a key transcriptional regulator involved in the complex growth cycle of Streptomyces. Streptomyces are Gram-positive bacteria well-known for their production of secondary metabolites and antibiotics. Most work...
3.
Guyet A, Gominet M, Benaroudj N, Mazodier P
Arch Microbiol . 2013 Nov; 195(12):831-41. PMID: 24196782
Insertion of an apramycin resistance cassette in the clpP1clpP2 operon (encoding the ClpP1 and ClpP2 peptidase subunits) affects morphological and physiological differentiation of Streptomyces lividans. Another key factor controlling Streptomyces...
4.
Gominet M, Seghezzi N, Mazodier P
Microbiology (Reading) . 2011 Jun; 157(Pt 8):2226-2234. PMID: 21636652
ADEP, a molecule of the acyl depsipeptide family, has an antibiotic activity with a unique mode of action. ADEP binding to the ubiquitous protease ClpP alters the structure of the...
5.
Ratelade J, Miot M, Johnson E, Betton J, Mazodier P, Benaroudj N
Appl Environ Microbiol . 2009 Apr; 75(11):3803-7. PMID: 19346357
To eliminate unavoidable contamination of purified recombinant proteins by DnaK, we present a unique approach employing a BL21(DE3) DeltadnaK strain of Escherichia coli. Selected representative purified proteins remained soluble, correctly...
6.
Bellier A, Gominet M, Mazodier P
Microbiology (Reading) . 2006 Mar; 152(Pt 4):1021-1027. PMID: 16549666
It has been shown previously that expression of the Streptomyces lividans clpP1P2 operon, encoding proteolytic subunits of the Clp complex, the clpC1 gene, encoding the ATPase subunit, and the lon...
7.
Braud S, Lavire C, Bellier A, Mazodier P
Arch Microbiol . 2005 Nov; 184(6):343-52. PMID: 16308686
ssrA genes encoding tmRNA with transfer and messenger RNA functions are ubiquitous in bacteria. In a process called trans-translation, tmRNA enters a stalled ribosome and allows release of the original...
8.
Bellier A, Mazodier P
J Bacteriol . 2004 May; 186(10):3238-48. PMID: 15126487
The clp genes encoding the Clp proteolytic complex are widespread among living organisms. Five clpP genes are present in Streptomyces. Among them, the clpP1 clpP2 operon has been shown to...
9.
Sobczyk A, Bellier A, Viala J, Mazodier P
Microbiology (Reading) . 2002 Jun; 148(Pt 6):1931-1937. PMID: 12055312
Members of a family of ATP-dependent proteases related to Lon from Escherichia coli are present in most prokaryotes and eukaryotes. These proteases are generally reported to be heat induced, and...
10.
Viala J, Mazodier P
Mol Microbiol . 2002 May; 44(3):633-43. PMID: 11994147
Five clpP genes have been identified in Streptomyces coelicolor. The clpP1 and clpP2 genes form one operon, the clpP3 and clpP4 genes form another, and clpP5 is monocistronic. Previous studies...