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Philippe Lluel

Explore the profile of Philippe Lluel including associated specialties, affiliations and a list of published articles. Areas
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Articles 28
Citations 380
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Recent Articles
1.
Auge C, Vogt M, Martin V, Lezmi S, Game X, Lluel P, et al.
J Neural Transm (Vienna) . 2025 Mar; PMID: 40089646
While interstitial cystitis along with bladder pain syndrome (IC/BPS) is still poorly treated, published clinical evidence suggests that onabotulinumtoxinA (natural botulinum neurotoxin type A (BoNT/A)) intradetrusor injections is efficient in...
2.
Sens-Albert C, Weisenburger S, Konig B, Melcher S, Scheyhing U, Rollet K, et al.
Front Pharmacol . 2024 Apr; 15:1379456. PMID: 38560358
Phytotherapeutics, particularly extracts from (saw palmetto) fruit or (stinging nettle) root, are popular for the treatment of male lower urinary symptoms in many countries, but their mechanism of action is...
3.
Beraud C, Bidan N, Lassalle M, Lang H, Lindner V, Krucker C, et al.
Front Oncol . 2023 Jun; 13:1130048. PMID: 37305585
Background: Despite the significant advances in the management of advanced prostate cancer (PCa), metastatic PCa is currently considered incurable. For further investigations in precision treatment, the development of preclinical models...
4.
Resta J, Santin Y, Roumiguie M, Riant E, Lucas A, Couderc B, et al.
Int J Mol Sci . 2022 Oct; 23(19). PMID: 36233054
Bladder cancer is the 10th most common cancer in the world and has a high risk of recurrence and metastasis. In order to sustain high energetic needs, cancer cells undergo...
5.
Lang H, Beraud C, Cabel L, Fontugne J, Lassalle M, Krucker C, et al.
Front Oncol . 2022 Aug; 12:930731. PMID: 36033544
Background: Muscle-invasive bladder cancer (MIBC) and upper urinary tract urothelial carcinoma (UTUC) are molecularly heterogeneous. Despite chemotherapies, immunotherapies, or anti-fibroblast growth factor receptor (FGFR) treatments, these tumors are still of...
6.
Auge C, Dizeyi N, Ramnemark L, Lluel P, Grabe M
Scand J Urol . 2022 Jun; 56(4):320-328. PMID: 35766197
Objective: Inflammation of the urinary bladder may cause burdensome pain also called bladder pain syndrome (BPS). A limitation in understanding BPS pathophysiology is the lack of appropriate preclinical model. Previously...
7.
Auge C, Basso L, Blanpied C, Vergnolle N, Game X, Chabot S, et al.
Front Pain Res (Lausanne) . 2022 Mar; 2:642706. PMID: 35295433
Current analgesic treatments for Interstitial CystitisBladder Pain Syndrome (IC/BPS) are limited. Here, we propose a novel antinociceptive strategy exploiting the opioid-mediated analgesic properties of T lymphocytes to relieve from bladder...
8.
Santin Y, Lluel P, Rischmann P, Game X, Mialet-Perez J, Parini A
Cells . 2020 Nov; 9(11). PMID: 33167349
Cellular senescence is a state of cell cycle arrest induced by repetitive cell mitoses or different stresses, which is implicated in various physiological or pathological processes. The beneficial or adverse...
9.
Auge C, Game X, Vergnolle N, Lluel P, Chabot S
Front Pharmacol . 2020 Sep; 11:1305. PMID: 32982733
Interstitial cystitis/Bladder Pain Syndrome (IC/BPS) is a chronic inflammatory disease characterized by visceral pain and voiding symptoms. IC/BPS is still an unsolved enigma with ineffective diagnosis criteria and treatment. A...
10.
dAldebert E, Quaranta M, Sebert M, Bonnet D, Kirzin S, Portier G, et al.
Front Cell Dev Biol . 2020 Jun; 8:363. PMID: 32582690
Inflammatory Bowel Diseases (IBD) are chronic inflammatory disorders, where epithelial defects drive, at least in part, some of the pathology. We reconstituted human intestinal epithelial organ, by using three-dimension culture...