Philippe Brulet
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Explore the profile of Philippe Brulet including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
275
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0
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Recent Articles
1.
Lesne A, Rouquette O, Touzet S, Petit-Laurent F, Tourlonias G, Pasquion A, et al.
Endoscopy
. 2017 Apr;
49(8):765-775.
PMID: 28399611
Clinical Trials Registration: EudraCT 2012-A00548 - 35; NCT01937429.
2.
Gealageas R, Malikova N, Picaud S, Borgdorff A, Burakova L, Brulet P, et al.
Anal Bioanal Chem
. 2014 Feb;
406(11):2695-707.
PMID: 24553660
The main analytical use of Ca(2+)-regulated photoproteins from luminous coelenterates is for real-time non-invasive visualization of intracellular calcium concentration ([Ca(2+)]i) dynamics in cells and whole organisms. A limitation of this...
3.
Rogers K, Martin J, Renaud O, Karplus E, Nicola M, Nguyen M, et al.
J Biomed Opt
. 2008 Jul;
13(3):031211.
PMID: 18601535
The construction and application of genetically encoded intracellular calcium concentration ([Ca2+]i) indicators has a checkered history. Excitement raised over the creation of new probes is often followed by disappointment when...
4.
Rogers K, Picaud S, Roncali E, Boisgard R, Colasante C, Stinnakre J, et al.
PLoS One
. 2007 Oct;
2(10):e974.
PMID: 17912353
Rapid and transient elevations of Ca(2+) within cellular microdomains play a critical role in the regulation of many signal transduction pathways. Described here is a genetic approach for non-invasive detection...
5.
Agulhon C, Platel J, Kolomiets B, Forster V, Picaud S, Brocard J, et al.
J Physiol
. 2007 Jul;
583(Pt 3):945-58.
PMID: 17627996
Glial Ca(2+) excitability plays a key role in reciprocal neuron-glia communication. In the retina, neuron-glia signalling is expected to be maximal in the dark, but the glial Ca(2+) signal characteristics...
6.
Martin J, Rogers K, Chagneau C, Brulet P
PLoS One
. 2007 Mar;
2(3):e275.
PMID: 17342209
Many different cells' signalling pathways are universally regulated by Ca(2+) concentration [Ca(2+)] rises that have highly variable amplitudes and kinetic properties. Optical imaging can provide the means to characterise both...
7.
Curie T, Rogers K, Colasante C, Brulet P
Mol Imaging
. 2007 Feb;
6(1):30-42.
PMID: 17311763
Real-time visualization of calcium (Ca(2+)) dynamics in the whole animal will enable important advances in understanding the complexities of cellular function. The genetically encoded bioluminescent Ca(2+) reporter green fluorescent protein-aequorin...
8.
Roux S, Saint Cloment C, Curie T, Girard E, Miana Mena F, Barbier J, et al.
Eur J Neurosci
. 2006 Sep;
24(6):1546-54.
PMID: 17004918
In a previous study it was reported that fusion proteins composed of the atoxic C-terminal fragment of tetanus toxin (TTC) and green fluorescent protein or beta-galactosidase (GFP-TTC and beta-gal-TTC, respectively)...
9.
Miana-Mena F, Munoz M, Roux S, Ciriza J, Zaragoza P, Brulet P, et al.
Neurodegener Dis
. 2006 Aug;
1(2-3):101-8.
PMID: 16908981
Gene therapy vectors that can be targeted to motoneuronal cells are required in the field of neurodegenerative diseases. We propose the use of the atoxic fragment C of tetanus toxin...
10.
Roux S, Colasante C, Saint Cloment C, Barbier J, Curie T, Girard E, et al.
Mol Cell Neurosci
. 2006 Feb;
30(4):572-82.
PMID: 16456925
The distribution, dynamics, internalization, and retrograde axonal traffic of a fusion protein composed of green fluorescent protein (GFP)and the atoxic C-terminal fragment of tetanus toxin (TTC) were studied after its...