Philipp Schwintek
Overview
Explore the profile of Philipp Schwintek including associated specialties, affiliations and a list of published articles.
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5
Citations
51
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Recent Articles
1.
Calaca Serrao A, Wunnava S, Dass A, Ufer L, Schwintek P, Mast C, et al.
J Am Chem Soc
. 2024 Mar;
146(13):8887-8894.
PMID: 38503430
Templated ligation offers an efficient approach to replicate long strands in an RNA world. The 2',3'-cyclic phosphate (>P) is a prebiotically available activation that also forms during RNA hydrolysis. Using...
2.
Bartolucci G, Calaca Serrao A, Schwintek P, Kuhnlein A, Rana Y, Janto P, et al.
Proc Natl Acad Sci U S A
. 2023 Oct;
120(43):e2218876120.
PMID: 37847736
The emergence of functional oligonucleotides on early Earth required a molecular selection mechanism to screen for specific sequences with prebiotic functions. Cyclic processes such as daily temperature oscillations were ubiquitous...
3.
Tekin E, Salditt A, Schwintek P, Wunnava S, Langlais J, Saenz J, et al.
Chembiochem
. 2022 Nov;
23(24):e202200423.
PMID: 36354762
When water interacts with porous rocks, its wetting and surface tension properties create air bubbles in large number. To probe their relevance as a setting for the emergence of life,...
4.
Morasch M, Liu J, Dirscherl C, Ianeselli A, Kuhnlein A, Le Vay K, et al.
Nat Chem
. 2019 Jul;
11(9):779-788.
PMID: 31358919
Non-equilibrium conditions must have been crucial for the assembly of the first informational polymers of early life, by supporting their formation and continuous enrichment in a long-lasting environment. Here, we...
5.
Edeleva E, Salditt A, Stamp J, Schwintek P, Boekhoven J, Braun D
Chem Sci
. 2019 Jul;
10(22):5807-5814.
PMID: 31293769
Continuous enzyme-free replication of oligonucleotides is central for open-ended evolution experiments that mimic the origin of life. Here, we studied a reaction system, whereby two 24mer DNA templates cross-catalyzed each...