Philipp Schreppel
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Explore the profile of Philipp Schreppel including associated specialties, affiliations and a list of published articles.
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6
Citations
68
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Recent Articles
1.
Luo L, Wang J, Ding D, Hasan M, Yang S, Lin S, et al.
Front Physiol
. 2020 Aug;
11:911.
PMID: 32848856
Na-K-2Cl cotransporter isoform 1 (NKCC1) is important in regulating intracellular K and Cl homeostasis and cell volume. In this study, we investigated a role of NKCC1 in regulating glioma K...
2.
Auer T, Schreppel P, Erker T, Schwarzer C
Pharmacol Ther
. 2019 Oct;
205:107422.
PMID: 31626872
Epilepsies represent one of the most common neurological diseases worldwide. They are characterized by recurrent spontaneous seizures with severe impact on a patient's life. An imbalance in excitatory and inhibitory...
3.
Auer T, Schreppel P, Erker T, Schwarzer C
Neuropharmacology
. 2019 Sep;
162:107754.
PMID: 31476353
Temporal lobe epilepsy (TLE) is the most common type of focal epilepsies, affecting approximately 35 million people worldwide. Despite the introduction of numerous novel antiepileptic drugs during the last decades,...
4.
Huang H, Bhuiyan M, Jiang T, Song S, Shankar S, Taheri T, et al.
Stroke
. 2019 Mar;
50(4):1021-1025.
PMID: 30862257
Background and Purpose- Inhibition of brain NKCC1 (Na-K-Cl cotransporter 1) with bumetanide (BMT) is of interest in ischemic stroke therapy. However, its poor brain penetration limits the application. In this...
5.
Kloesch B, Loebsch S, Breitenbach J, Goldhahn K, Handler N, Schreppel P, et al.
Nat Prod Commun
. 2018 Dec;
11(10):1437-1440.
PMID: 30549594
Genistein, a naturally occurring isoflavone, possesses many beneficial health effects. To improve the bioactivity of the natural compound, we designed and synthesized the genistein prodrug FEHH6-1. In the present study,...
6.
Erker T, Brandt C, Tollner K, Schreppel P, Twele F, Schidlitzki A, et al.
Epilepsia
. 2016 Feb;
57(5):698-705.
PMID: 26921222
Objective: The loop diuretic bumetanide has been reported to potentiate the antiseizure activity of phenobarbital in rodent models of neonatal seizures, most likely as a result of inhibition of the...