Philip V Holmes
Overview
Explore the profile of Philip V Holmes including associated specialties, affiliations and a list of published articles.
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42
Citations
1050
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Recent Articles
1.
Kaimal A, Hooversmith J, Al Mansi M, Cherry A, Garrity J, Holmes P, et al.
Front Endocrinol (Lausanne)
. 2025 Jan;
15():1479838.
PMID: 39839474
Significance: Women are at increased risk for mood disorders, which may be partly attributed to exposure to endocrine-disrupting chemicals (EDCs) during sensitive periods such as pregnancy. Exposure during these times...
2.
Kaimal A, Hooversmith J, Al Mansi M, Holmes P, MohanKumar P, MohanKumar S
J Xenobiot
. 2024 Aug;
14(3):1036-1050.
PMID: 39189173
This study examines the sex-specific effects of gestational exposure (days 6-21) to endocrine-disrupting chemicals such as bisphenol A (BPA), diethylhexyl phthalate (DEHP), or their combination on brain monoamine levels that...
3.
Kaimal A, Hooversmith J, Cherry A, Garrity J, Al Mansi M, Martin N, et al.
Front Toxicol
. 2023 Dec;
5:1264238.
PMID: 38152552
Prenatal exposures to endocrine disrupting chemicals (EDCs) are correlated with adverse behavioral outcomes, but the effects of combinations of these chemicals are unclear. The aim of this study was to...
4.
Kim J, Williams K, Kirkland R, Schade R, Freeman K, Cawthon C, et al.
Mol Metab
. 2023 Jun;
75:101764.
PMID: 37380023
Objective: Our goal is to investigate if microbiota composition modulates reward signaling and assess the role of the vagus in mediating microbiota to brain communication. Methods: Male germ-free Fisher rats...
5.
Latchoumane C, Betancur M, Simchick G, Sun M, Forghani R, Lenear C, et al.
Sci Adv
. 2021 Mar;
7(10).
PMID: 33674306
Severe traumatic brain injury (sTBI) survivors experience permanent functional disabilities due to significant volume loss and the brain's poor capacity to regenerate. Chondroitin sulfate glycosaminoglycans (CS-GAGs) are key regulators of...
6.
Tillage R, Wilson G, Liles L, Holmes P, Weinshenker D
J Neurosci
. 2020 Sep;
40(39):7464-7474.
PMID: 32868458
The neuropeptide galanin has been implicated in stress-related neuropsychiatric disorders in humans and rodent models. While pharmacological treatments for these disorders are ineffective for many individuals, physical activity is beneficial...
7.
Sun M, Passaro A, Latchoumane C, Spellicy S, Bowler M, Goeden M, et al.
J Neurotrauma
. 2019 Nov;
37(11):1358-1369.
PMID: 31774030
The lack of effective therapies for moderate-to-severe traumatic brain injuries (TBIs) leaves patients with lifelong disabilities. Neural stem cells (NSCs) have demonstrated great promise for neural repair and regeneration. However,...
8.
Hooversmith J, Bhatti D, Holmes P
Behav Brain Res
. 2019 Aug;
375:112160.
PMID: 31434003
The neuropeptide galanin is a potential therapeutic target for treating stress-related disorders, such as post-traumatic stress disorder (PTSD); however, its effects on contextual fear conditioning (CFC), an accepted animal model...
9.
Stringham N, Holmes P, Stringham J
Physiol Behav
. 2019 Aug;
211:112650.
PMID: 31425700
Purpose: Oxidative and inflammatory processes play a major role in stress-induced neural atrophy. There is a wide body of literature linking oxidative and inflammatory stress with reductions in neurotrophic factors,...
10.
Stringham N, Holmes P, Stringham J
Nutr Neurosci
. 2017 Feb;
21(4):286-296.
PMID: 28198205
Purpose: Oxidative stress and systemic inflammation are the root cause of several deleterious effects of chronic psychological stress. We hypothesize that the antioxidant and anti-inflammatory capabilities of the macular carotenoids...