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Philip T Liu

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Articles 38
Citations 4581
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Recent Articles
1.
Gottlieb C, Henrich M, Liu P, Yacoubian V, Wang J, Chun R, et al.
Nutrients . 2023 Mar; 15(6). PMID: 36986109
Vitamin D is known to modulate human immune responses, and vitamin D deficiency is associated with increased susceptibility to infection. However, what constitutes sufficient levels or whether vitamin D is...
2.
Kim E, De Leon A, Jiang Z, Radu R, Martineau A, Chan E, et al.
mSphere . 2019 Jun; 4(3). PMID: 31167948
Epidemiological evidence correlates low serum vitamin A (retinol) levels with increased susceptibility to active tuberculosis (TB); however, retinol is biologically inactive and must be converted into its bioactive form, all-...
3.
Zavala K, Gottlieb C, Teles R, Adams J, Hewison M, Modlin R, et al.
PLoS Negl Trop Dis . 2018 Oct; 12(10):e0006815. PMID: 30300363
Following infection, virulent mycobacteria persist and grow within the macrophage, suggesting that the intrinsic activation of an innate antimicrobial response is subverted by the intracellular pathogen. For Mycobacterium leprae, the...
4.
Kim E, Teles R, Haile S, Liu P, Modlin R
PLoS Negl Trop Dis . 2018 Jul; 12(7):e0006608. PMID: 29965969
Background: The immune system depends on effector pathways to eliminate invading pathogens from the host in vivo. Macrophages (MΦ) of the innate immune system are armed with vitamin D-dependent antimicrobial...
5.
Park A, Agak G, Qin M, Hisaw L, Pirouz A, Kao S, et al.
Ann Dermatol . 2017 Dec; 29(6):688-698. PMID: 29200756
Background: Acne vulgaris is a disease of the pilosebaceous unit characterized by increased sebum production, hyperkeratinization, and immune responses to (PA). Here, we explore a possible mechanism by which a...
6.
Realegeno S, Kelly-Scumpia K, Dang A, Lu J, Teles R, Liu P, et al.
PLoS Pathog . 2016 Jun; 12(6):e1005705. PMID: 27355424
Triggering antimicrobial mechanisms in macrophages infected with intracellular pathogens, such as mycobacteria, is critical to host defense against the infection. To uncover the unique and shared antimicrobial networks induced by...
7.
Kim E, Nadipuram S, Tetlow A, Barshop W, Liu P, Wohlschlegel J, et al.
mSphere . 2016 Jun; 1(2). PMID: 27303719
Toxoplasma gondii uses unique secretory organelles called rhoptries to inject an array of effector proteins into the host cytoplasm that hijack host cell functions. We have discovered a novel rhoptry...
8.
Adams J, Ramin J, Rafison B, Windon C, Windon A, Liu P
Bone Res . 2014 Oct; 1(1):2-10. PMID: 25285234
No abstract available.
9.
Mehta M, Liu P
Front Genet . 2014 Aug; 5:231. PMID: 25076967
As the role of microRNA in all aspects of biology continues to be unraveled, the interplay between microRNAs and human disease is becoming clearer. It should come of no surprise...
10.
Chun R, Liu P, Modlin R, Adams J, Hewison M
Front Physiol . 2014 May; 5:151. PMID: 24795646
Immunomodulatory responses to the active form of vitamin D (1,25-dihydroxyvitamin D, 1,25D) have been recognized for many years, but it is only in the last 5 years that the potential...