Philip R L Parker
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Explore the profile of Philip R L Parker including associated specialties, affiliations and a list of published articles.
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12
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1885
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Recent Articles
1.
Martins D, Manda J, Goard M, Parker P
Curr Biol
. 2024 Dec;
34(23):R1185-R1202.
PMID: 39626632
Determining the location of objects relative to ourselves is essential for interacting with the world. Neural activity in the retina is used to form a vision-independent model of the local...
2.
Parker P, Martins D, Leonard E, Casey N, Sharp S, Abe E, et al.
Nat Neurosci
. 2023 Nov;
26(12):2192-2202.
PMID: 37996524
Animals move their head and eyes as they explore the visual scene. Neural correlates of these movements have been found in rodent primary visual cortex (V1), but their sources and...
3.
Parker P, Abe E, Leonard E, Martins D, Niell C
Neuron
. 2022 Sep;
110(23):3897-3906.e5.
PMID: 36137549
Visual input during natural behavior is highly dependent on movements of the eyes and head, but how information about eye and head position is integrated with visual processing during free...
4.
Parker P, Abe E, Beatie N, Leonard E, Martins D, Sharp S, et al.
Elife
. 2022 Sep;
11.
PMID: 36125119
In natural contexts, sensory processing and motor output are closely coupled, which is reflected in the fact that many brain areas contain both sensory and movement signals. However, standard reductionist...
5.
Tomorsky J, Parker P, Doe C, Niell C
Neural Dev
. 2020 Nov;
15(1):13.
PMID: 33160402
Background: Developing cortical neurons express a tightly choreographed sequence of cytoskeletal and transmembrane proteins to form and strengthen specific synaptic connections during circuit formation. Nectin-3 is a cell-adhesion molecule with...
6.
Parker P, Brown M, Smear M, Niell C
Trends Neurosci
. 2020 Jun;
43(8):581-595.
PMID: 32580899
Recent studies have demonstrated prominent and widespread movement-related signals in the brain of head-fixed mice, even in primary sensory areas. However, it is still unknown what role these signals play...
7.
Michaiel A, Parker P, Niell C
Cell Rep
. 2019 Mar;
26(13):3475-3483.e4.
PMID: 30917304
Sensory perception arises from the integration of externally and internally driven representations of the world. Disrupted balance of these representations can lead to perceptual deficits and hallucinations. The serotonin-2A receptor...
8.
Parker P, Lalive A, Kreitzer A
Neuron
. 2016 Feb;
89(4):734-40.
PMID: 26833136
Movement suppression in Parkinson's disease (PD) is thought to arise from increased efficacy of the indirect pathway basal ganglia circuit, relative to the direct pathway. However, the underlying pathophysiological mechanisms...
9.
Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation
Harwell C, Parker P, Gee S, Okada A, McConnell S, Kreitzer A, et al.
Neuron
. 2012 Mar;
73(6):1116-26.
PMID: 22445340
The precise connectivity of inputs and outputs is critical for cerebral cortex function; however, the cellular mechanisms that establish these connections are poorly understood. Here, we show that the secreted...
10.
Kravitz A, Freeze B, Parker P, Kay K, Thwin M, Deisseroth K, et al.
Nature
. 2010 Jul;
466(7306):622-6.
PMID: 20613723
Neural circuits of the basal ganglia are critical for motor planning and action selection. Two parallel basal ganglia pathways have been described, and have been proposed to exert opposing influences...