Philip R Baldwin
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Explore the profile of Philip R Baldwin including associated specialties, affiliations and a list of published articles.
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Recent Articles
1.
Fischer Q, Kalikulov D, Di Prisco G, Williams C, Baldwin P, Friedlander M
J Neurotrauma
. 2024 May;
41(21-22):2455-2477.
PMID: 38818799
Neurostimulation protocols are increasingly used as therapeutic interventions, including for brain injury. In addition to the direct activation of neurons, these stimulation protocols are also likely to have downstream effects...
2.
Kleywegt G, Adams P, Butcher S, Lawson C, Rohou A, Rosenthal P, et al.
IUCrJ
. 2024 Feb;
11(Pt 2):140-151.
PMID: 38358351
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for the deposition and validation of cryoEM structures, with a focus on single-particle analysis. The...
3.
Aiyer S, Baldwin P, Tan S, Shan Z, Oh J, Mehrani A, et al.
Nat Commun
. 2024 Jan;
15(1):389.
PMID: 38195598
Structural biology efforts using cryogenic electron microscopy are frequently stifled by specimens adopting "preferred orientations" on grids, leading to anisotropic map resolution and impeding structure determination. Tilting the specimen stage...
4.
Kleywegt G, Adams P, Butcher S, Lawson C, Rohou A, Rosenthal P, et al.
ArXiv
. 2023 Dec;
PMID: 38076521
In January 2020, a workshop was held at EMBL-EBI (Hinxton, UK) to discuss data requirements for deposition and validation of cryoEM structures, with a focus on single-particle analysis. The meeting...
5.
Aiyer S, Baldwin P, Tan S, Shan Z, Oh J, Mehrani A, et al.
bioRxiv
. 2023 Jul;
PMID: 37503021
Structural biology efforts using cryogenic electron microscopy are frequently stifled by specimens adopting "preferred orientations" on grids, leading to anisotropic map resolution and impeding structure determination. Tilting the specimen stage...
6.
Baldwin P
J Struct Biol X
. 2023 Jul;
7:100089.
PMID: 37398937
Correlation functions play an important role in the theoretical underpinnings of many disparate areas of the physical sciences: in particular, scattering theory. More recently, they have become useful in the...
7.
Baldwin P, Lyumkis D
Prog Biophys Mol Biol
. 2020 Jul;
160:53-65.
PMID: 32645314
A complete understanding of how an orientation distribution contributes to a cryo-EM reconstruction remains lacking. It is necessary to begin critically assessing the set of views to gain an understanding...
8.
Baldwin P, Lyumkis D
Prog Biophys Mol Biol
. 2019 Sep;
150:160-183.
PMID: 31525386
Virtually all single-particle cryo-EM experiments currently suffer from specimen adherence to the air-water interface, leading to a non-uniform distribution in the set of projection views. Whereas it is well accepted...
9.
Baldwin P, Tan Y, Eng E, Rice W, Noble A, Negro C, et al.
Curr Opin Microbiol
. 2017 Nov;
43:1-8.
PMID: 29100109
The scope and complexity of cryogenic electron microscopy (cryoEM) data has greatly increased, and will continue to do so, due to recent and ongoing technical breakthroughs that have led to...
10.
Abdallah C, Averill C, Salas R, Averill L, Baldwin P, Krystal J, et al.
Biol Psychiatry Cogn Neurosci Neuroimaging
. 2017 Oct;
2(7):566-574.
PMID: 29034354
Background: Prefrontal global brain connectivity with global signal regression (GBCr) was proposed as a robust biomarker of depression, and was associated with ketamine's mechanism of action. Here, we investigated prefrontal...