Philip M Hansbro
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Explore the profile of Philip M Hansbro including associated specialties, affiliations and a list of published articles.
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Recent Articles
21.
Mac Aogain M, Tiew P, Jaggi T, Narayana J, Singh S, Hansbro P, et al.
Expert Rev Respir Med
. 2024 May;
18(3-4):111-125.
PMID: 38743428
Introduction: This review summarizes our current understanding of the respiratory microbiome in COPD and Bronchiectasis. We explore the interplay between microbial communities, host immune responses, disease pathology, and treatment outcomes....
22.
Jha S, De Rubis G, Devkota S, Zhang Y, Adhikari R, Jha L, et al.
Ageing Res Rev
. 2024 Apr;
97:102315.
PMID: 38679394
Lung cancer stands as the primary contributor to cancer-related fatalities worldwide, affecting both genders. Two primary types exist where non-small cell lung cancer (NSCLC), accounts for 80-85% and SCLC accounts...
23.
Saeid A, De Rubis G, Williams K, Yeung S, Chellappan D, Singh S, et al.
Chem Biol Interact
. 2024 Apr;
395:111009.
PMID: 38641145
The escalating prevalence of lung diseases underscores the need for innovative therapies. Dysbiosis in human body microbiome has emerged as a significant factor in these diseases, indicating a potential role...
24.
Wang Y, Thaler M, Salgado-Benvindo C, Ly N, Leijs A, Ninaber D, et al.
Clin Transl Immunology
. 2024 Apr;
13(4):e1503.
PMID: 38623540
Objectives: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a member of a class of highly pathogenic coronaviruses. The large family of coronaviruses, however, also includes members that cause only...
25.
Idrees S, Chen H, Panth N, Paudel K, Hansbro P
Microorganisms
. 2024 Mar;
12(3).
PMID: 38543681
The interactions between human and viral proteins are pivotal in viral infection and host immune responses. These interactions traverse different stages of the viral life cycle, encompassing initial entry into...
26.
Eapen M, Lu W, Dey S, Chia C, Hardikar A, Hassan M, et al.
ERJ Open Res
. 2024 Mar;
10(2).
PMID: 38500797
Background: COPD patients suffer from dysregulated and suppressed immune functionality, determined by their loss of degranulating capacity. Here we provide crucial information on the presence of degranulated mast cells (MCs)...
27.
Pathinayake P, Hsu A, Nichol K, Horvat J, Hansbro P, Wark P
Am J Physiol Lung Cell Mol Physiol
. 2024 Mar;
326(5):L618-L626.
PMID: 38469627
Thymic stromal lymphopoietin (TSLP) is an epithelial-derived pleiotropic cytokine that regulates T-helper 2 (Th2) immune responses in the lung and plays a major role in severe uncontrolled asthma. Emerging evidence...
28.
Idrees S, Paudel K, Sadaf T, Hansbro P
FEBS Lett
. 2024 Mar;
598(7):725-742.
PMID: 38439692
Protein-protein interactions (PPIs) are often mediated by short linear motifs (SLiMs) in one protein and domain in another, known as domain-motif interactions (DMIs). During the past decade, SLiMs have been...
29.
Idrees S, Paudel K, Hansbro P
Arch Microbiol
. 2024 Feb;
206(3):94.
PMID: 38334822
One of the mechanisms viruses use in hijacking host cellular machinery is mimicking Short Linear Motifs (SLiMs) in host proteins to maintain their life cycle inside host cells. In the...
30.
Budden K, Shukla S, Bowerman K, Vaughan A, Gellatly S, Wood D, et al.
Gut
. 2024 Feb;
73(5):751-769.
PMID: 38331563
Objective: Chronic obstructive pulmonary disease (COPD) is a major cause of global illness and death, most commonly caused by cigarette smoke. The mechanisms of pathogenesis remain poorly understood, limiting the...