Philip G Allen
Overview
Explore the profile of Philip G Allen including associated specialties, affiliations and a list of published articles.
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14
Citations
547
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Recent Articles
1.
Suki B, Hu Y, Murata N, Imsirovic J, Mondonedo J, de Oliveira C, et al.
Sci Rep
. 2017 May;
7(1):2305.
PMID: 28536424
There is growing interest in quantifying vascular cell and tissue stiffness. Most measurement approaches, however, are incapable of assessing stiffness in the presence of physiological flows. We developed a microfluidic...
2.
Bartolak-Suki E, Imsirovic J, Parameswaran H, Wellman T, Martinez N, Allen P, et al.
Nat Mater
. 2015 Jul;
14(10):1049-57.
PMID: 26213900
Cells can be exposed to irregular mechanical fluctuations, such as those arising from changes in blood pressure. Here, we report that ATP production, assessed through changes in mitochondrial membrane potential,...
3.
Suki B, Jesudason R, Sato S, Parameswaran H, Araujo A, Majumdar A, et al.
Pulm Pharmacol Ther
. 2011 Apr;
25(4):268-75.
PMID: 21514397
Emphysema is a disease of the lung parenchyma with progressive alveolar tissue destruction that leads to peripheral airspace enlargement. In this review, we discuss how mechanical forces can contribute to...
4.
Jesudason R, Sato S, Parameswaran H, Araujo A, Majumdar A, Allen P, et al.
Biophys J
. 2010 Nov;
99(9):3076-83.
PMID: 21044606
Many fundamental cellular and extracellular processes in the body are mediated by enzymes. At the single molecule level, enzyme activity is influenced by mechanical forces. However, the effects of mechanical...
5.
Appel S, Allen P, Vetterkind S, Jin J, Morgan K
Mol Biol Cell
. 2010 Feb;
21(8):1409-22.
PMID: 20181831
Migration of fibroblasts is important in wound healing. Here, we demonstrate a role and a mechanism for h3/acidic calponin (aCaP, CNN3) in REF52.2 cell motility, a fibroblast line rich in...
6.
Parameswaran H, Bartolak-Suki E, Hamakawa H, Majumdar A, Allen P, Suki B
J Appl Physiol (1985)
. 2009 Jun;
107(2):583-92.
PMID: 19541732
In pulmonary emphysema, the alveolar structure progressively breaks down via a three-dimensional (3D) process that leads to airspace enlargement. The characterization of such structural changes has, however, been based on...
7.
Nehilla B, Allen P, Desai T
ACS Nano
. 2009 Feb;
2(3):538-44.
PMID: 19206580
Nanoprecipitation was utilized to synthesize biodegradable and surfactant-free nanoparticles loaded with quantum dots. This protocol also yielded nanoparticles coloaded with both quantum dots and hydrophobic drug (Coenzyme Q10) molecules. Importantly,...
8.
Black L, Allen P, Morris S, Stone P, Suki B
Biophys J
. 2007 Nov;
94(5):1916-29.
PMID: 17993498
The goal of this study was to determine how alterations in protein composition of the extracellular matrix (ECM) affect its functional properties. To achieve this, we investigated the changes in...
9.
Kiener H, Stipp C, Allen P, Higgins J, Brenner M
Mol Biol Cell
. 2006 Mar;
17(5):2366-76.
PMID: 16525026
Cadherins mediate homophilic cell adhesion and contribute to tissue morphogenesis and architecture. Cadherin cell adhesion contacts are actively remodeled and impact cell movement and migration over other cells. We found...
10.
Cicchetti G, Biernacki M, Farquharson J, Allen P
Biochemistry
. 2004 Feb;
43(7):1939-49.
PMID: 14967034
Phosphoinositides are important signal transduction intermediates in cell growth, survival, and motility. We have invented a fluorescence sensor for polyphosphorylated phosphoinositides based on a peptide derived from the Listeria protein...