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Philip D Coblentz

Explore the profile of Philip D Coblentz including associated specialties, affiliations and a list of published articles. Areas
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Citations 46
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Recent Articles
1.
Coblentz P, Ahn B, Hayward L, Yoo J, Christou D, Ferreira L
Am J Physiol Lung Cell Mol Physiol . 2019 Feb; 316(4):L679-L690. PMID: 30702345
Heart failure with reduced ejection fraction (HFREF) increases neutral sphingomyelinase (NSMase) activity and mitochondrial reactive oxygen species (ROS) emission and causes diaphragm weakness. We tested whether a systemic pharmacological NSMase...
2.
Ahn B, Coblentz P, Beharry A, Patel N, Judge A, Moylan J, et al.
Front Physiol . 2017 Jan; 7:686. PMID: 28119629
Patients with heart failure (HF) have diaphragm abnormalities that contribute to disease morbidity and mortality. Studies in animals suggest that reactive oxygen species (ROS) cause diaphragm abnormalities in HF. However,...
3.
Laitano O, Ahn B, Patel N, Coblentz P, Smuder A, Yoo J, et al.
J Appl Physiol (1985) . 2016 Feb; 120(7):733-42. PMID: 26846552
Diaphragm muscle weakness in chronic heart failure (CHF) is caused by elevated oxidants and exacerbates breathing abnormalities, exercise intolerance, and dyspnea. However, the specific source of oxidants that cause diaphragm...