Petra Leyendecker
Overview
Explore the profile of Petra Leyendecker including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
295
Followers
0
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Recent Articles
1.
Ahmedzai S, Nauck F, Bar-Sela G, Bosse B, Leyendecker P, Hopp M
Palliat Med
. 2011 Sep;
26(1):50-60.
PMID: 21937568
Objective: An examination of whether oxycodone/naloxone prolonged-release tablets (OXN PR) can improve constipation and maintain analgesia, compared with oxycodone prolonged-release tablets (OxyPR) in patients with moderate/severe cancer pain. Methods: Randomized,...
2.
Lowenstein O, Leyendecker P, Lux E, Blagden M, Simpson K, Hopp M, et al.
BMC Clin Pharmacol
. 2010 Oct;
10:12.
PMID: 20920236
Background: Two randomised 12-week, double-blind, parallel-group, multicenter studies comparing oxycodone PR/naloxone PR and oxycodone PR alone on symptoms of opioid-induced bowel dysfunction in patients with moderate/severe non-malignant pain have been...
3.
Holzer P, Ahmedzai S, Niederle N, Leyendecker P, Hopp M, Bosse B, et al.
J Opioid Manag
. 2009 Aug;
5(3):145-51.
PMID: 19662924
Opioids are the mainstay of management for patients with cancer-related pain. Although the analgesic efficacy of opioid therapy is well documented, the recent European Pain in Cancer survey demonstrated that...
4.
Smith K, Hopp M, Mundin G, Leyendecker P, Bailey P, Grothe B, et al.
Clin Ther
. 2008 Dec;
30(11):2051-68.
PMID: 19108793
Background: There is an increasing body of evidence supporting the need for prophylactic management of the adverse events (AEs) associated with long-term opioid use in patients with chronic pain. Symptoms...
5.
Reimer K, Hopp M, Zenz M, Maier C, Holzer P, Mikus G, et al.
Pharmacology
. 2008 Oct;
83(1):10-7.
PMID: 18957874
Opioid analgesics are the cornerstone of pain management for moderate-to-severe cancer pain and, increasingly, chronic noncancer pain. Despite proven analgesic efficacy, the use of opioids is commonly associated with frequently...
6.
Meissner W, Leyendecker P, Mueller-Lissner S, Nadstawek J, Hopp M, Ruckes C, et al.
Eur J Pain
. 2008 Sep;
13(1):56-64.
PMID: 18762438
Background: Opioid-induced constipation can have a major negative impact on patients' quality of life. This randomised, double-blinded study evaluated the analgesic efficacy of prolonged-release (PR) oral oxycodone when co-administered with...
7.
Vondrackova D, Leyendecker P, Meissner W, Hopp M, Szombati I, Hermanns K, et al.
J Pain
. 2008 Aug;
9(12):1144-54.
PMID: 18708300
Unlabelled: This randomized, double-blind, placebo- and active-controlled, parallel-group study was designed to demonstrate the superiority of oxycodone in combination with naloxone in a prolonged release (PR) formulation over placebo with...