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Petr Ponomarenko

Explore the profile of Petr Ponomarenko including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 21
Citations 180
Followers 0
Related Specialties
Molecular Biology
Biochemistry
Chemistry
Top 10 Co-Authors
Mikhail Ponomarenko
Ludmila Savinkova
Irina Chadaeva
Dmitry Rasskazov
Nikolay Kolchanov
Ekaterina Sharypova
Dmitry Oshchepkov
Irina Drachkova
Anton Bogomolov
Olga Podkolodnaya
Published In
Int J Mol Sci
Front Genet
Biomed Res Int
PLoS One
Front Immunol
Affiliations
Soon will be listed here.
Recent Articles
1.
AtSNP_TATAdb: Candidate Molecular Markers of Plant Advantages Related to Single Nucleotide Polymorphisms within Proximal Promoters of L
Bogomolov A, Zolotareva K, Filonov S, Chadaeva I, Rasskazov D, Sharypova E, et al.
Int J Mol Sci . 2024 Jan; 25(1). PMID: 38203780
The mainstream of the post-genome target-assisted breeding in crop plant species includes biofortification such as high-throughput phenotyping along with genome-based selection. Therefore, in this work, we used the Web-service Plant_SNP_TATA_Z-tester,...
2.
Candidate SNP Markers Significantly Altering the Affinity of TATA-Binding Protein for the Promoters of Human Hub Genes for Atherogenesis, Atherosclerosis and Atheroprotection
Bogomolov A, Filonov S, Chadaeva I, Rasskazov D, Khandaev B, Zolotareva K, et al.
Int J Mol Sci . 2023 May; 24(10). PMID: 37240358
Atherosclerosis is a systemic disease in which focal lesions in arteries promote the build-up of lipoproteins and cholesterol they are transporting. The development of atheroma (atherogenesis) narrows blood vessels, reduces...
3.
Plant_SNP_TATA_Z-Tester: A Web Service That Unequivocally Estimates the Impact of Proximal Promoter Mutations on Plant Gene Expression
Rasskazov D, Chadaeva I, Sharypova E, Zolotareva K, Khandaev B, Ponomarenko P, et al.
Int J Mol Sci . 2022 Aug; 23(15). PMID: 35955817
Synthetic targeted optimization of plant promoters is becoming a part of progress in mainstream postgenomic agriculture along with hybridization of cultivated plants with wild congeners, as well as marker-assisted breeding....
4.
Stress Reactivity, Susceptibility to Hypertension, and Differential Expression of Genes in Hypertensive Compared to Normotensive Patients
Oshchepkov D, Chadaeva I, Kozhemyakina R, Zolotareva K, Khandaev B, Sharypova E, et al.
Int J Mol Sci . 2022 Mar; 23(5). PMID: 35269977
Although half of hypertensive patients have hypertensive parents, known hypertension-related human loci identified by genome-wide analysis explain only 3% of hypertension heredity. Therefore, mainstream transcriptome profiling of hypertensive subjects addresses...
5.
Domestication Explains Two-Thirds of Differential-Gene-Expression Variance between Domestic and Wild Animals; The Remaining One-Third Reflects Intraspecific and Interspecific Variation
Chadaeva I, Ponomarenko P, Kozhemyakina R, Suslov V, Bogomolov A, Klimova N, et al.
Animals (Basel) . 2021 Sep; 11(9). PMID: 34573632
Belyaev's concept of destabilizing selection during domestication was a major achievement in the XX century. Its practical value has been realized in commercial colors of the domesticated fox that never...
6.
Disruptive Selection of Human Immunostimulatory and Immunosuppressive Genes Both Provokes and Prevents Rheumatoid Arthritis, Respectively, as a Self-Domestication Syndrome
Klimova N, Oshchepkova E, Chadaeva I, Sharypova E, Ponomarenko P, Drachkova I, et al.
Front Genet . 2021 Jul; 12:610774. PMID: 34239535
Using our previously published Web service SNP_TATA_Comparator, we conducted a genome-wide study of single-nucleotide polymorphisms (SNPs) within core promoters of 68 human rheumatoid arthritis (RA)-related genes. Using 603 SNPs within...
7.
A Bioinformatics Model of Human Diseases on the Basis of Differentially Expressed Genes (of Domestic Versus Wild Animals) That Are Orthologs of Human Genes Associated with Reproductive-Potential Changes
Vasiliev G, Chadaeva I, Rasskazov D, Ponomarenko P, Sharypova E, Drachkova I, et al.
Int J Mol Sci . 2021 Mar; 22(5). PMID: 33652917
Earlier, after our bioinformatic analysis of single-nucleotide polymorphisms of TATA-binding protein-binding sites within gene promoters on the human Y chromosome, we suggested that human reproductive potential diminishes during self-domestication. Here,...
8.
Unannotated single nucleotide polymorphisms in the TATA box of erythropoiesis genes show in vitro positive involvements in cognitive and mental disorders
Ponomarenko M, Sharypova E, Drachkova I, Chadaeva I, Arkova O, Podkolodnaya O, et al.
BMC Med Genet . 2020 Oct; 21(Suppl 1):165. PMID: 33092544
Background: Hemoglobin is a tetramer consisting of two α-chains and two β-chains of globin. Hereditary aberrations in the synthesis of one of the globin chains are at the root of...
9.
Disruptive natural selection by male reproductive potential prevents underexpression of protein-coding genes on the human Y chromosome as a self-domestication syndrome
Ponomarenko M, Kleshchev M, Ponomarenko P, Chadaeva I, Sharypova E, Rasskazov D, et al.
BMC Genet . 2020 Oct; 21(Suppl 1):89. PMID: 33092533
Background: In population ecology, the concept of reproductive potential denotes the most vital indicator of chances to produce and sustain a healthy descendant until his/her reproductive maturity under the best...
10.
Candidate SNP Markers of Atherogenesis Significantly Shifting the Affinity of TATA-Binding Protein for Human Gene Promoters show stabilizing Natural Selection as a Sum of Neutral Drift Accelerating Atherogenesis and Directional Natural Selection...
Ponomarenko M, Rasskazov D, Chadaeva I, Sharypova E, Drachkova I, Oshchepkov D, et al.
Int J Mol Sci . 2020 Feb; 21(3). PMID: 32033288
(1) Background: The World Health Organization (WHO) regards atherosclerosis-related myocardial infarction and stroke as the main causes of death in humans. Susceptibility to atherogenesis-associated diseases is caused by single-nucleotide polymorphisms...