Peter R Bar
Overview
Explore the profile of Peter R Bar including associated specialties, affiliations and a list of published articles.
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9
Citations
376
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Recent Articles
1.
de Winter F, Vo T, Stam F, Wisman L, Bar P, Niclou S, et al.
Mol Cell Neurosci
. 2006 May;
32(1-2):102-17.
PMID: 16677822
Neuromuscular synapses differ markedly in their plasticity. Motor nerve terminals innervating slow muscle fibers sprout vigorously following synaptic blockage, while those innervating fast-fatigable muscle fibers fail to exhibit any sprouting....
2.
Groeneveld G, van Muiswinkel F, de Leeuw van Weenen J, Blauw H, Veldink J, Wokke J, et al.
Amyotroph Lateral Scler Other Motor Neuron Disord
. 2005 Apr;
5(4):220-5.
PMID: 15799550
Background: There is an accumulating body of evidence that apoptosis is involved in the motor neuron death that occurs in ALS, and in the (G93A) mSOD1 transgenic mouse model (mSOD1...
3.
Wisman L, van Muiswinkel F, de Graan P, Hol E, Bar P
Neuroreport
. 2003 Oct;
14(15):1967-70.
PMID: 14561930
Amyotrophic lateral sclerosis is an incurable disease in which cerebral and spinal motoneurons degenerate, causing paralysis and death within 2-5 years. One of the pathogenic factors of motoneuron death is...
4.
Kuo J, Schonewille M, Siddique T, Schults A, Fu R, Bar P, et al.
J Neurophysiol
. 2003 Oct;
91(1):571-5.
PMID: 14523070
ALS (amyotrophic lateral sclerosis) is an adult-onset and deadly neurodegenerative disease characterized by a progressive and selective loss of motoneurons. Transgenic mice overexpressing a mutated human gene (G93A) coding for...
5.
Veldhuis W, Floris S, van der Meide P, Vos I, de Vries H, Dijkstra C, et al.
J Cereb Blood Flow Metab
. 2003 Sep;
23(9):1060-9.
PMID: 12973022
Inflammation can contribute to brain injury, such as that resulting from ischemia or trauma. The authors have previously shown that the cytokine interferon-beta (IFN-beta) affords protection against ischemic brain injury,...
6.
Veldhuis W, Derksen J, Floris S, van der Meide P, de Vries H, Schepers J, et al.
J Cereb Blood Flow Metab
. 2003 Sep;
23(9):1029-39.
PMID: 12973019
The inflammatory response that exacerbates cerebral injury after ischemia is an attractive therapeutic target: it progresses over days and strongly contributes to worsening of the neurologic outcome. The authors show...
7.
van der Stelt M, Hansen H, Veldhuis W, Bar P, Nicolay K, Veldink G, et al.
Neurotox Res
. 2003 Jul;
5(3):183-200.
PMID: 12835123
Endocannabinoids are thought to function as retrograde messengers, which modulate neurotransmitter release by activating presynaptic cannabinoid receptors. Anandamide and 2-arachidonoylglycerol (2-AG) are the two best studied endogenous lipids which can...
8.
Veldhuis W, van der Stelt M, Delmas F, Gillet B, Veldink G, Vliegenthart J, et al.
J Cereb Blood Flow Metab
. 2002 Dec;
23(1):62-74.
PMID: 12500092
The susceptibility of immature rat brain to neurotoxicity of N-methyl-D-aspartate (NMDA) has provided a widely used paradigm to study excitotoxicity relevant to acute neurodegenerative diseases such as cerebral ischemia. In...
9.
van der Stelt M, Veldhuis W, Maccarrone M, Bar P, Nicolay K, Veldink G, et al.
Mol Neurobiol
. 2002 Nov;
26(2-3):317-46.
PMID: 12428763
The endocannabinoid system is a valuable target for drug discovery, because it is involved in the regulation of many cellular and physiological functions. The endocannabinoid system constitutes the endogenous lipids...