Peter P Nawroth
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Explore the profile of Peter P Nawroth including associated specialties, affiliations and a list of published articles.
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256
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9712
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Recent Articles
1.
Schwarz D, Le Marois M, Sturm V, Peters A, Longuespee R, Helm D, et al.
Diabetes
. 2024 Oct;
74(1):65-74.
PMID: 39418320
Article Highlights:
2.
Kumar V, Yildirim A, Nawroth P
Nat Rev Endocrinol
. 2024 Sep;
20(11):629-630.
PMID: 39266727
No abstract available.
3.
Rhein S, Costalunga R, Inderhees J, Gurtzgen T, Faupel T, Shaheryar Z, et al.
Nat Commun
. 2024 Jul;
15(1):5745.
PMID: 38987239
Complications of diabetes are often attributed to glucose and reactive dicarbonyl metabolites derived from glycolysis or gluconeogenesis, such as methylglyoxal. However, in the CNS, neurons and endothelial cells use lactate...
4.
von Rauchhaupt E, Rodemer C, Kliemank E, Bulkescher R, Campos M, Kopf S, et al.
Diabetes Care
. 2024 Jun;
47(9):1584-1592.
PMID: 38905209
Objective: Prolonged catabolic states in type 2 diabetes (T2D), exacerbated by excess substrate flux and hyperglycemia, can challenge metabolic flexibility and antioxidative capacity. We investigated cellular responses to glucose load...
5.
Peter A, Schleicher E, Kliemank E, Szendroedi J, Konigsrainer A, Haring H, et al.
Metabolites
. 2024 Apr;
14(4).
PMID: 38668337
The underlying molecular mechanisms for the development of non-alcoholic fatty liver (NAFL) and its progression to advanced liver diseases remain elusive. Glyoxalase 1 (Glo1) loss, leading to elevated methylglyoxal (MG)...
6.
Harrer P, Inderhees J, Zhao C, Schormair B, Tilch E, Gieger C, et al.
EBioMedicine
. 2024 Feb;
101:105007.
PMID: 38354534
Background: The dicarbonyl compounds methylglyoxal (MG), glyoxal (GO) and 3-deoxyglucosone (3-DG) have been linked to various diseases. However, disease-independent phenotypic and genotypic association studies with phenome-wide and genome-wide reach, respectively,...
7.
Schimpfle L, Tsilingiris D, Mooshage C, Kender Z, Sulaj A, von Rauchhaupt E, et al.
J Clin Endocrinol Metab
. 2024 Jan;
109(11):e2110-e2119.
PMID: 38215056
Context: Due to the heterogenous clinical symptoms and deficits, the diagnosis of diabetic polyneuropathy (DPN) is still difficult in clinical routines, leading to increased morbidity and mortality. Objective: We studied...
8.
Seizer P, von Ungern-Sternberg S, Haug V, Dicenta V, Rosa A, Butt E, et al.
Cardiovasc Res
. 2024 Jan;
120(4):385-402.
PMID: 38175781
Aims: Cyclophilin A (CyPA) induces leucocyte recruitment and platelet activation upon release into the extracellular space. Extracellular CyPA therefore plays a critical role in immuno-inflammatory responses in tissue injury and...
9.
Brings S, Mier W, Beijer B, Kliemank E, Herzig S, Szendroedi J, et al.
Biochem J
. 2023 Dec;
481(1):33-44.
PMID: 38112318
Advanced glycation end products (AGEs) are non-enzymatic post-translational modifications of amino acids and are associated with diabetic complications. One proposed pathomechanism is the impaired processing of AGE-modified proteins or peptides...
10.
Malyukov M, Gelfgat E, Ruiz-Babot G, Schmid J, Lehmann S, Spinas G, et al.
Xenotransplantation
. 2023 Aug;
30(5):e12819.
PMID: 37548062
Primary adrenal insufficiency is a life-threatening disorder, which requires lifelong hormone replacement therapy. Transplantation of xenogeneic adrenal cells is a potential alternative approach for the treatment of adrenal insufficiency. For...