Peter L Delputte
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Explore the profile of Peter L Delputte including associated specialties, affiliations and a list of published articles.
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42
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1432
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Recent Articles
11.
Van der Gucht W, Leemans A, De Schryver M, Heykers A, Caljon G, Maes L, et al.
Virol J
. 2017 Aug;
14(1):157.
PMID: 28818113
Background: Host proteases have been shown to play important roles in many viral activities such as entry, uncoating, viral protein production and disease induction. Therefore, these cellular proteases are putative...
12.
De Schryver M, Cappoen D, Elewaut D, Nauwynck H, Maes L, Caljon G, et al.
Cell Immunol
. 2016 Dec;
312:51-60.
PMID: 27993350
Sialoadhesin (Sn) is a surface receptor expressed on macrophages in steady state conditions, but during inflammation, Sn can be upregulated both on macrophages and on circulating monocytes. It was shown...
13.
De Schryver M, Leemans A, Pintelon I, Cappoen D, Maes L, Caljon G, et al.
Immunobiology
. 2016 Dec;
222(6):797-806.
PMID: 27899210
Sialoadhesin (Sn) is a surface receptor expressed on resident macrophages with the ability to bind with sialic acids. During inflammation, an upregulation of Sn is observed. Upon binding of monoclonal...
14.
Ooms K, Van Gorp H, Botti S, Van Gaever T, Delputte P, Nauwynck H
Virus Res
. 2013 Aug;
177(2):147-55.
PMID: 23932898
Targeting antigens to professional antigen presenting cells resident at the sites where effective immune responses are generated is a promising vaccination strategy. As such, targeting sialoadhesin (Sn)-expressing macrophages, abundantly present...
15.
Ooms K, Van Gorp H, Van Gaever T, Nauwynck H, Delputte P
BMC Biotechnol
. 2013 Apr;
13:33.
PMID: 23575465
Background: Sialoadhesin (Sn)-expressing monocytes/macrophages have been associated with several diseases like inflammatory and autoimmune disorders as well as viral infections, and they also appear to play a role in the...
16.
De Baere M, Van Gorp H, Delputte P, Nauwynck H
Vet Res
. 2012 May;
43:47.
PMID: 22630829
Porcine reproductive and respiratory syndrome virus (PRRSV) is an arterivirus that shows a restricted in vivo tropism for subsets of porcine macrophages, with alveolar macrophages being major target cells. The...
17.
Saha D, Lefebvre D, Ooms K, Huang L, Delputte P, Van Doorsselaere J, et al.
J Gen Virol
. 2012 Apr;
93(Pt 7):1548-1555.
PMID: 22492916
Porcine circovirus 2 (PCV2) is the causative agent of porcine circovirus-associated diseases in pigs. Previously, it was demonstrated that mAbs 16G12, 38C1, 63H3 and 94H8 directed against the PCV2 capsid...
18.
De Baere M, Van Gorp H, Nauwynck H, Delputte P
Cell Immunol
. 2011 Sep;
271(2):462-73.
PMID: 21944562
Sialoadhesin (Sn) is a macrophage-restricted endocytic receptor involved in cell-cell, cell-matrix and cell-pathogen interactions. Recently, porcine Sn (pSn) was shown to be involved in signaling and lately Sn is gaining...
19.
Van Doorsselaere J, Geldhof M, Nauwynck H, Delputte P
Virol J
. 2011 Apr;
8:160.
PMID: 21477345
PRRS is a pig disease of major economic importance that causes respiratory and reproductive problems in pigs. Over the last years it has become clear that PRRSV heterogeneity is increasing....
20.
Delputte P, Van Gorp H, Favoreel H, Hoebeke I, Delrue I, Dewerchin H, et al.
PLoS One
. 2011 Mar;
6(2):e16827.
PMID: 21359217
Sialoadhesin is exclusively expressed on specific subpopulations of macrophages. Since sialoadhesin-positive macrophages are involved in inflammatory autoimmune diseases, such as multiple sclerosis, and potentially in the generation of immune responses,...