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Peter Kuckenberg

Explore the profile of Peter Kuckenberg including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 341
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Recent Articles
1.
Kubaczka C, Senner C, Cierlitza M, Arauzo-Bravo M, Kuckenberg P, Peitz M, et al.
Cell Stem Cell . 2015 Sep; 17(5):557-68. PMID: 26412560
Trophoblast stem cells (TSCs) arise from the first cell fate decision in the developing embryo and generate extra-embryonic lineages, giving rise to the fetal portion of the placenta. Mouse embryonic...
2.
Kaiser S, Koch Y, Kuhnel E, Sharma N, Gellhaus A, Kuckenberg P, et al.
Biol Reprod . 2015 Jun; 93(2):31. PMID: 26063869
Tfap2c is required for placental development and trophoblast stem cell maintenance. Deletion of Tfap2c results in early embryonic loss because of failure in placental development. We evaluated the effect of...
3.
Kubaczka C, Senner C, Arauzo-Bravo M, Sharma N, Kuckenberg P, Becker A, et al.
Stem Cell Reports . 2014 Feb; 2(2):232-42. PMID: 24527396
Trophoblast stem cells (TSCs) are in vitro equivalents to the precursor cells of the placenta. TSCs are cultured in serum-rich medium with fibroblast growth factor 4, heparin, and embryonic-fibroblast-conditioned medium....
4.
Kuckenberg P, Kubaczka C, Schorle H
Reprod Biomed Online . 2012 May; 25(1):12-20. PMID: 22560121
In recent years, knowledge regarding the genetic and epigenetic programmes governing specification, maintenance and differentiation of the extraembryonic lineage has advanced substantially. Establishment and analysis of mice deficient in genes...
5.
Holl D, Kuckenberg P, Woynecki T, Egert A, Becker A, Huss S, et al.
PLoS One . 2011 Jul; 6(7):e22034. PMID: 21779369
Background: The transcription factor Tcfap2c has been demonstrated to be essential for various processes during mammalian development. It has been found to be upregulated in various undifferentiated tumors and is...
6.
Kuckenberg P, Peitz M, Kubaczka C, Becker A, Egert A, Wardelmann E, et al.
Mol Cell Biol . 2011 Feb; 31(8):1748-56. PMID: 21300784
In mammals, the first cell fate decision is initialized by cell polarization at the 8- to 16-cell stage of the preimplantation embryo. At this stage, outside cells adopt a trophectoderm...
7.
Kuckenberg P, Buhl S, Woynecki T, van Furden B, Tolkunova E, Seiffe F, et al.
Mol Cell Biol . 2010 Apr; 30(13):3310-20. PMID: 20404091
In mammals, cell lineage specification is established at the blastocyst stage. At this stage, transcription factor Cdx2 represses pluripotency genes, thus promoting extraembryonic trophoblast fate. Recently, transcription factor Gata3 was...
8.
Weber S, Eckert D, Nettersheim D, Gillis A, Schafer S, Kuckenberg P, et al.
Biol Reprod . 2009 Sep; 82(1):214-23. PMID: 19776388
Formation of the germ cell lineage involves multiple processes, including repression of somatic differentiation and reacquisition of pluripotency as well as a unique epigenetic constitution. The transcriptional regulator Prdm1 has...