Peter K Rogan
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Explore the profile of Peter K Rogan including associated specialties, affiliations and a list of published articles.
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68
Citations
896
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Recent Articles
1.
Shirley B, Mucaki E, Knoll J, Rogan P
Radiat Prot Dosimetry
. 2023 Sep;
199(14):1465-1471.
PMID: 37721084
Rapid sample processing and interpretation of estimated exposures will be critical for triaging exposed individuals after a major radiation incident. The dicentric chromosome (DC) assay assesses absorbed radiation using metaphase...
2.
Mucaki E, Shirley B, Rogan P
F1000Res
. 2022 Aug;
10:1312.
PMID: 35646330
This study aimed to produce community-level geo-spatial mapping of confirmed COVID-19 cases in Ontario Canada in near real-time to support decision-making. This was accomplished by area-to-area geostatistical analysis, space-time integration,...
3.
Bagchee-Clark A, Mucaki E, Whitehead T, Rogan P
MedComm (2020)
. 2021 Nov;
1(3):311-327.
PMID: 34766125
Cancer chemotherapy responses have been related to multiple pharmacogenetic biomarkers, often for the same drug. This study utilizes machine learning to derive multi-gene expression signatures that predict individual patient responses...
4.
Mucaki E, Shirley B, Rogan P
Int J Radiat Biol
. 2021 Oct;
98(5):924-941.
PMID: 34699300
Purpose: Combinations of expressed genes can discriminate radiation-exposed from normal control blood samples by machine learning (ML) based signatures (with 8-20% misclassification rates). These signatures can quantify therapeutically relevant as...
5.
Hill S, Rogan P, Wang Y, Knoll J
Mol Cytogenet
. 2021 Oct;
14(1):49.
PMID: 34670606
Background: During mitosis, chromatin engages in a dynamic cycle of condensation and decondensation. Condensation into distinct units to ensure high fidelity segregation is followed by rapid and reproducible decondensation to...
6.
Ostheim P, Amundson S, Badie C, Bazyka D, Evans A, Ghandhi S, et al.
Int J Radiat Biol
. 2021 Oct;
98(5):843-854.
PMID: 34606416
Purpose: In a nuclear or radiological event, an early diagnostic or prognostic tool is needed to distinguish unexposed from low- and highly exposed individuals with the latter requiring early and...
7.
Rogan P, Mucaki E, Shirley B
F1000Res
. 2021 Jan;
9:943.
PMID: 33299552
Certain riboviruses can cause severe pulmonary complications leading to death in some infected patients. We propose that DNA damage induced-apoptosis accelerates viral release, triggered by depletion of host RNA binding...
8.
Shirley B, Knoll J, Moquet J, Ainsbury E, Pham N, Norton F, et al.
Int J Radiat Biol
. 2020 Sep;
96(11):1492-1503.
PMID: 32910711
Purpose: Inhomogeneous exposures to ionizing radiation can be detected and quantified with the dicentric chromosome assay (DCA) of metaphase cells. Complete automation of interpretation of the DCA for whole-body irradiation...
9.
Rao S, Pitel B, Wagner A, Boca S, McCoy M, King I, et al.
JCO Clin Cancer Inform
. 2020 Jul;
4:602-613.
PMID: 32644817
Purpose: The cancer research community is constantly evolving to better understand tumor biology, disease etiology, risk stratification, and pathways to novel treatments. Yet the clinical cancer genomics field has been...
10.
Rogan P, Mucaki E, Lu R, Shirley B, Waller E, Knoll J
PLoS One
. 2020 Apr;
15(4):e0232008.
PMID: 32330192
Background: Accurate radiation dose estimates are critical for determining eligibility for therapies by timely triaging of exposed individuals after large-scale radiation events. However, the universal assessment of a large population...