Peter K Jeffery
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Explore the profile of Peter K Jeffery including associated specialties, affiliations and a list of published articles.
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44
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2049
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Recent Articles
1.
Zhu J, Edwards M, Message S, Stanciu L, Johnston S, Jeffery P
Pharmaceuticals (Basel)
. 2024 Nov;
17(11).
PMID: 39598462
Cilomilast, a phosphodiesterase-4 (PDE4) selective inhibitor, has anti-inflammatory effects in vitro and in vivo and reduces COPD exacerbations. We tested the hypothesis that cilomilast inhibits virus-induced airway epithelial intercellular adhesion...
2.
Zhu J, Mallia P, Footitt J, Qiu Y, Message S, Kebadze T, et al.
J Allergy Clin Immunol
. 2020 Apr;
146(4):840-850.e7.
PMID: 32283204
Background: Respiratory viral infection causes chronic obstructive pulmonary disease (COPD) exacerbations. We previously reported increased bronchial mucosa eosinophil and neutrophil inflammation in patients with COPD experiencing naturally occurring exacerbations. But...
3.
Zhu J, Message S, Mallia P, Kebadze T, Contoli M, Ward C, et al.
J Allergy Clin Immunol
. 2018 Apr;
143(1):114-125.e4.
PMID: 29698627
Background: The innate immune system senses viral infection through pattern recognition receptors (PRRs), leading to type I interferon production. The role of type I interferon and PPRs in rhinovirus-induced asthma...
4.
Zhu J, Message S, Qiu Y, Mallia P, Kebadze T, Contoli M, et al.
Chest
. 2014 Jan;
145(6):1219-1229.
PMID: 24457412
Background: The nature of bronchial mucosal inflammation and its physiologic and clinical significance in rhinovirus-induced asthma exacerbations is unclear. We investigated bronchial mucosal inflammatory response and its association with physiologic...
5.
Agusti A, Barbera J, Wouters E, Peinado V, Jeffery P
Am J Respir Crit Care Med
. 2013 Nov;
188(12):1396-406.
PMID: 24175885
Patients with chronic obstructive pulmonary disease (COPD) often suffer other concomitant disorders, such as cardiovascular diseases and metabolic disorders, that influence significantly (and independently of lung function) their health status...
6.
OReilly R, Ullmann N, Irving S, Bossley C, Sonnappa S, Zhu J, et al.
J Allergy Clin Immunol
. 2012 Oct;
131(4):1024-32, 1032.e1-16.
PMID: 23069488
Background: Increased airway smooth muscle (ASM) is a feature of established asthma in schoolchildren, but nothing is known about ASM in preschool wheezers. Objective: We sought to determine endobronchial biopsy...
7.
Zhu J, Bandi V, Qiu S, Figueroa D, Evans J, Barnes N, et al.
Chest
. 2012 Aug;
142(2):347-357.
PMID: 22871757
Background: Cysteinyl leukotriene 1 (CysLT1) receptor expression is known to be increased in the airway mucosa of patients with asthma, especially during exacerbations; however, nothing is known of its expression...
8.
Regamey N, Tsartsali L, Hilliard T, Fuchs O, Tan H, Zhu J, et al.
Thorax
. 2011 Oct;
67(2):164-70.
PMID: 22008188
Background: Studies in cystic fibrosis (CF) generally focus on inflammation present in the airway lumen. Little is known about inflammation occurring in the airway wall, the site ultimately destroyed in...
9.
Tsartsali L, Hislop A, Mckay K, James A, Elliot J, Zhu J, et al.
Thorax
. 2011 Jan;
66(4):280-5.
PMID: 21233480
Background: The bronchial epithelium and underlying reticular basement membrane (RBM) have a close spatial and functional inter-relationship and are considered an epithelial-mesenchymal trophic unit (EMTU). An understanding of RBM development...
10.
Malmstrom K, Pelkonen A, Malmberg L, Sarna S, Lindahl H, Kajosaari M, et al.
Thorax
. 2011 Jan;
66(2):157-62.
PMID: 21199817
Background: Relationships between early deficits of lung function, infant airway pathology and outcome in symptomatic infants are unclear. A study was undertaken to determine the associations between early lung function,...