Peter J West
Overview
Explore the profile of Peter J West including associated specialties, affiliations and a list of published articles.
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30
Citations
586
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Recent Articles
1.
Wooley J, Zachery-Savella A, Le M, Scofield S, Jay K, Mosse-Robinson J, et al.
bioRxiv
. 2025 Mar;
PMID: 40027820
Objective: Epilepsy is characterised by unprovoked and recurring seizures, which can be electrically measured using electroencephalograms (EEG). To better understand the underlying mechanisms of seizures, researchers are exploring their temporal...
2.
Moncion C, West P, Metcalf C
Epilepsy Curr
. 2024 Nov;
24(5):355-357.
PMID: 39508005
No abstract available.
3.
Jackson H, Cotler M, Saunders G, Cornelssen C, West P, Metcalf C, et al.
Brain
. 2024 Sep;
147(12):4147-4156.
PMID: 39241108
Focal epilepsy is a difficult disease to treat as two-thirds of patients will not respond to oral anti-seizure medications (ASMs) or have severe off-target effects that lead to drug discontinuation....
4.
Jakubiec M, Abram M, Zagaja M, Socala K, Panic V, Latacz G, et al.
ACS Chem Neurosci
. 2024 Aug;
15(17):3228-3256.
PMID: 39166702
We developed a focused series of original phenyl-glycinamide derivatives which showed potent activity across mouse seizure models, namely, maximal electroshock (MES) and 6 Hz (using both 32 and 44 mA...
5.
Giangrasso D, Veros K, Timm M, West P, Wilcox K, Keefe K
Front Mol Neurosci
. 2023 May;
16:1160157.
PMID: 37251646
The shift from drug abuse to addiction is considered to arise from the transition between goal-directed and habitual control over drug behavior. Habitual responding for appetitive and skill-based behaviors is...
6.
Heruye S, Warren T, Kostansek Iv J, Draves S, Matthews S, West P, et al.
Nutrients
. 2022 Mar;
14(3).
PMID: 35276972
Ascorbic acid (AA; a.k.a. vitamin C) is well known for its cellular protection in environments of high oxidative stress. Even though physiological concentrations of AA in the brain are significant...
7.
Gibson A, West P, Keefe K
Psychopharmacology (Berl)
. 2022 Jan;
239(1):93-104.
PMID: 34985532
Rationale: Methamphetamine (METH) exposure is associated with damage to central monoamine systems, particularly dopamine signaling. Rodent models of such damage have revealed a decrease in the amplitude of phasic dopamine...
8.
West P, Thomson K, Billingsley P, Pruess T, Rueda C, Saunders G, et al.
Exp Neurol
. 2021 Dec;
349:113954.
PMID: 34922908
The discovery and development of novel antiseizure drugs (ASDs) that are effective in controlling pharmacoresistant spontaneous recurrent seizures (SRSs) continues to represent a significant unmet clinical need. The Epilepsy Therapy...
9.
Metcalf C, Vanegas F, Underwood T, Johnson K, West P, Smith M, et al.
Epilepsia Open
. 2021 Oct;
7(1):46-58.
PMID: 34668659
Objective: Infection with Theiler's murine encephalomyelitis virus (TMEV) in C57Bl/6J mice results in handling-induced seizures and is useful for evaluating compounds effective against infection-induced seizures. However, to date only a...
10.
Pernici C, Mensah J, Dahle E, Johnson K, Handy L, Buxton L, et al.
Epilepsia
. 2021 May;
62(7):1665-1676.
PMID: 34002394
Objective: Dravet syndrome (DS) is a rare but catastrophic genetic epilepsy, with 80% of patients carrying a mutation in the SCN1A gene. Currently, no antiseizure drug (ASD) exists that adequately...