Peter J Nicholls
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Explore the profile of Peter J Nicholls including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
246
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0
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Recent Articles
1.
Jacobsen J, Oh A, Bangle R, Roberts W, Royer E, Modesto N, et al.
Neuropsychopharmacology
. 2019 Apr;
44(12):2082-2090.
PMID: 31035282
5-hydroxytryptophan (5-HTP) has shown therapeutic promise in a range of human CNS disorders. But native 5-HTP immediate release (IR) is poorly druggable, as rapid absorption causes rapid onset of adverse...
2.
Beraldo F, Ostapchenko V, Xu J, Di Guglielmo G, Fan J, Nicholls P, et al.
J Neurochem
. 2017 Dec;
145(1):68-79.
PMID: 29265373
Stress-inducible phosphoprotein 1 (STI1) acts as a neuroprotective factor in the ischemic brain and its levels are increased following ischemia. Previous work has suggested that some of these STI1 actions...
3.
Xie L, Dibb R, Cofer G, Li W, Nicholls P, Johnson G, et al.
Magn Reson Med
. 2014 Apr;
73(3):1270-81.
PMID: 24700637
Purpose: The purpose of this study was to determine whether susceptibility tensor imaging (STI) could overcome limitations of current techniques to detect tubules throughout the kidney. Methods: Normal mouse kidneys...
4.
Urs N, Nicholls P, Caron M
Curr Opin Cell Biol
. 2014 Apr;
27:56-62.
PMID: 24680431
The G-protein coupled receptor (GPCR) family of genes represents one of the largest druggable families of genes in the human genome. This is evident by the fact that approximately 30%...
5.
Salahpour A, Ramsey A, Medvedev I, Kile B, Sotnikova T, Holmstrand E, et al.
Proc Natl Acad Sci U S A
. 2008 Mar;
105(11):4405-10.
PMID: 18347339
The dopamine transporter (DAT) plays a key role in the regulation of dopaminergic signaling wherein it controls both the spatial and temporal actions of dopamine. Here we evaluated the behavioral...
6.
Badea A, Nicholls P, Johnson G, Wetsel W
Neuroimage
. 2006 Dec;
34(4):1363-74.
PMID: 17185001
The reeler mouse (Reln) has been proposed as a neurodevelopmental model for certain neurological and psychiatric conditions and has been studied by qualitative histochemistry and electron microscopy. Using magnetic resonance...
7.
Nicholls P, Abraham K, Connor K, Ross J, Davidson J
Compr Psychiatry
. 2005 Dec;
47(1):30-4.
PMID: 16324899
The Web site for the Anxiety Disorders Association of America (ADAA) receives more than 5 million visits per month and thus represents a unique medium for the study of anxiety...
8.
Emberson L, Trivett A, Blower P, Nicholls P
J Immunol Methods
. 2005 Sep;
305(2):135-51.
PMID: 16139294
CD33 is a cell surface glycoprotein expressed on cells of myelomonocytic lineage, leukaemic cells, but not haematopoietic stem cells. By virtue of its expression pattern, CD33 has become a popular...
9.
Ellery J, Nicholls P
Immunol Cell Biol
. 2002 Jul;
80(4):351-7.
PMID: 12121224
The receptors for interleukin 2 (IL-2) and interleukin 15 (IL-15) in T cells share the IL-2R beta subunit (CD122) and gamma(C) subunit but have private alpha subunits. Despite utilizing the...
10.
Ellery J, Nicholls P
Cytokine Growth Factor Rev
. 2001 Dec;
13(1):27-40.
PMID: 11750878
Interleukin-2 (IL-2) plays a major role in the proliferation of cell populations during an immune reaction. The beta(c) and gamma(c) subunits of the IL-2 receptor (IL-2R) are sufficient and necessary...