Peter J Eggenhuizen
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Explore the profile of Peter J Eggenhuizen including associated specialties, affiliations and a list of published articles.
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26
Citations
403
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Recent Articles
1.
Eggenhuizen P, Ng B, Lo C, Chang J, Snelgrove S, Cheong R, et al.
Kidney Int
. 2025 Jan;
PMID: 39842638
Anti-glomerular basement membrane (anti-GBM) disease is accompanied by insufficient antigen-specific regulatory T cells (Tregs) and clonally expanded antigen-specific conventional T cells. In particular, this applied to the immunodominant T cell...
2.
Gong Y, Meng T, Lin W, Hu X, Tang R, Xiong Q, et al.
Clin Kidney J
. 2024 Sep;
17(9):sfae264.
PMID: 39286239
Background: The remission rate of myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients who received standard induction therapy is far from satisfactory. Improving the remission rate of MPO-AAV patients is...
3.
Gong Y, Shen C, Meng T, Lin W, Hu X, Tang R, et al.
Clin Exp Med
. 2024 Apr;
24(1):66.
PMID: 38564029
Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) patients with dual positivity for proteinase 3-ANCA (PR3-ANCA) and myeloperoxidase-ANCA (MPO-ANCA) are uncommon. We aimed to investigate these idiopathic double-positive AAV patients' clinical features,...
4.
Eggenhuizen P, Ooi J
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540178
Memory T cells form from the adaptive immune response to historic infections or vaccinations. Some memory T cells have the potential to recognise unrelated pathogens like severe acute respiratory syndrome...
5.
Eggenhuizen P, Cheong R, Lo C, Chang J, Ng B, Ting Y, et al.
Nat Commun
. 2024 Feb;
15(1):899.
PMID: 38321013
Antigen-specific regulatory T cells (Tregs) suppress pathogenic autoreactivity and are potential therapeutic candidates for autoimmune diseases such as systemic lupus erythematosus (SLE). Lupus nephritis is associated with autoreactivity to the...
6.
Tang R, Lin W, Shen C, Hu X, Yu L, Meng T, et al.
Int Immunopharmacol
. 2023 Oct;
125(Pt A):111104.
PMID: 37897949
Hypertensive nephropathy (HTN) is one of the leading causes of end-stage renal disease, yet the molecular mechanisms are still unknown. To explore novel mechanisms and gene targets for HTN, the...
7.
Chen J, Meng T, Xu J, Ooi J, Eggenhuizen P, Liu W, et al.
Front Immunol
. 2023 Jul;
14:1084299.
PMID: 37503353
Background: Previous studies from our group and other investigators have shown that lung involvement is one of the independent predictors for treatment resistance in patients with myeloperoxidase (MPO)-anti-neutrophil cytoplasmic antibody...
8.
Hu X, Shen C, Meng T, Ooi J, Eggenhuizen P, Zhou Y, et al.
Front Immunol
. 2022 Nov;
13:991469.
PMID: 36389826
Background: Several lines of evidence implicate that there are distinct differences between patients with myeloperoxidase (MPO)-antineutrophil cytoplasmic antibody (ANCA) and anti-glomerular basement membrane (GBM) antibody double-seropositive patients (DPPs) and single-positive...
9.
Xiong Q, Lin W, Shen C, Meng T, Tang R, Ooi J, et al.
Immunol Res
. 2022 Oct;
71(1):1-14.
PMID: 36227529
Co-occurrence of anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) and IgA nephropathy (IgAN) is extremely uncommon. To date, only a few case reports have described such patients. Here, we describe the...
10.
Yu L, Lin W, Shen C, Meng T, Jin P, Ding X, et al.
Front Med (Lausanne)
. 2022 Aug;
9:869284.
PMID: 35935760
To date, the pathogenesis of hepatitis B virus (HBV)-associated membranous nephropathy (MN) remains elusive. This study aimed to decipher the etiopathogenesis of HBV-associated MN by performing single-cell RNA sequencing (scRNA-seq)...