Peter G Noakes
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Explore the profile of Peter G Noakes including associated specialties, affiliations and a list of published articles.
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76
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1815
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Recent Articles
1.
Sheremeta C, Yarlagadda S, Smythe M, Noakes P
Curr Drug Targets
. 2024 Aug;
25(13):885-908.
PMID: 39177131
The global burden of neurological disorders is evident, yet there remains limited efficacious therapeutics for their treatment. There is a growing recognition of the role of inflammation in diseases of...
2.
Fogarty M, Drieberg-Thompson J, Bellingham M, Noakes P
Front Neurol
. 2024 Aug;
15:1422943.
PMID: 39119557
In amyotrophic lateral sclerosis (ALS) tissue and the SOD1 mouse model at mid-disease, death of hypoglossal motor neurons (XII MNs) is evident. These XII MNs innervate the intrinsic and extrinsic...
3.
Cheung S, Willis E, Simmons D, Bellingham M, Noakes P
Neurobiol Dis
. 2024 Jul;
200:106614.
PMID: 39067491
Perineuronal nets (PNNs) are extracellular matrix structures that surround excitable neurons and their proximal dendrites. PNNs play an important role in neuroprotection against oxidative stress. Oxidative stress within motor neurons...
4.
Cheung S, Bhavnani E, Simmons D, Bellingham M, Noakes P
Neuropathol Appl Neurobiol
. 2024 May;
50(3):e12982.
PMID: 38742276
Aims: Perineuronal nets (PNNs) are an extracellular matrix structure that encases excitable neurons. PNNs play a role in neuroprotection against oxidative stress. Oxidative stress within motor neurons can trigger neuronal...
5.
Al-Mhanawi B, Marti M, Morrison S, Gupta P, Alani M, Noakes P, et al.
STAR Protoc
. 2023 Nov;
4(4):102725.
PMID: 37976154
In response to the scarcity of advanced in vitro models dedicated to human CNS white matter research, we present a protocol to generate neuroectoderm-derived embedding-free human brain organoids enriched with...
6.
Shi D, Wong J, Zhu K, Noakes P, Rammes G
Int J Mol Sci
. 2023 Jan;
24(2).
PMID: 36674434
It has been hypothesised that inhalational anaesthetics such as isoflurane (Iso) may trigger the pathogenesis of Alzheimer's disease (AD), while the gaseous anaesthetic xenon (Xe) exhibits many features of a...
7.
Chand K, Lee K, Lavidis N, Rodriguez-Valle M, Ijaz H, Koehbach J, et al.
Sci Rep
. 2022 Nov;
12(1):20636.
PMID: 36450730
No abstract available.
8.
Bolneo E, Chau P, Noakes P, Bellingham M
Int J Mol Sci
. 2022 Jul;
23(14).
PMID: 35887307
Normal development and function of the central nervous system involves a balance between excitatory and inhibitory neurotransmission. Activity of both excitatory and inhibitory neurons is modulated by inhibitory signalling of...
9.
Ding Q, Kesavan K, Lee K, Wimberger E, Robertson T, Gill M, et al.
Acta Neuropathol Commun
. 2022 Apr;
10(1):61.
PMID: 35468848
A central event in the pathogenesis of motor neuron disease (MND) is the loss of neuromuscular junctions (NMJs), yet the mechanisms that lead to this event in MND remain to...
10.
Yarlagadda S, Kulis C, Noakes P, Smythe M
Life (Basel)
. 2021 Sep;
11(9).
PMID: 34575143
Duchenne muscular dystrophy (DMD) is characterized by progressive muscle weakness and wasting due to the lack of dystrophin protein. The acute phase of DMD is characterized by muscle necrosis and...