Peter Feddema
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Explore the profile of Peter Feddema including associated specialties, affiliations and a list of published articles.
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12
Citations
560
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Recent Articles
1.
Schneider C, Feller M, Bauer D, Collet T, da Costa B, Auer R, et al.
PLoS One
. 2018 May;
13(4):e0196631.
PMID: 29709030
Objective: Guidelines for thyroid function evaluation recommend testing TSH first, then assessing fT4 only if TSH is out of the reference range (two-step), but many clinicians initially request both TSH...
2.
Brown S, Bremner A, Hadlow N, Feddema P, Leedman P, OLeary P, et al.
Clin Endocrinol (Oxf)
. 2016 May;
85(5):789-796.
PMID: 27197788
Background: The TSH-T4 relationship was thought to be inverse log-linear, but recent cross-sectional studies of selected populations report a complex, nonlinear relationship. The TSH-T4 relationship has not been evaluated in...
3.
Medici M, Porcu E, Pistis G, Teumer A, Brown S, Jensen R, et al.
PLoS Genet
. 2014 Mar;
10(2):e1004123.
PMID: 24586183
Autoimmune thyroid diseases (AITD) are common, affecting 2-5% of the general population. Individuals with positive thyroid peroxidase antibodies (TPOAbs) have an increased risk of autoimmune hypothyroidism (Hashimoto's thyroiditis), as well...
4.
Bremner A, Feddema P, Leedman P, Brown S, Beilby J, Lim E, et al.
J Clin Endocrinol Metab
. 2012 Feb;
97(5):1554-62.
PMID: 22344200
Context: In cross-sectional studies, serum TSH concentrations increase with age. This has not been examined longitudinally, and it is uncertain whether the TSH increase reflects healthy aging or occult thyroid...
5.
Bremner A, Feddema P, Joske D, Leedman P, OLeary P, Olynyk J, et al.
Clin Endocrinol (Oxf)
. 2011 Sep;
76(2):304-11.
PMID: 21913954
Objective: Hypothyroidism and hyperthyroidism are each associated with anaemia, but relationships between thyroid function and erythrocyte indices in euthyroid subjects have not been examined. The aim of this study was...
6.
Walsh J, Bremner A, Feddema P, Leedman P, Brown S, OLeary P
J Clin Endocrinol Metab
. 2010 Jan;
95(3):1095-104.
PMID: 20097710
Context: Longitudinal studies of risk factors for hypothyroidism are required to inform debate regarding the TSH reference range. There are limited longitudinal data on the predictive value of thyroid antibodies...
7.
Makepeace A, Bremner A, OLeary P, Leedman P, Feddema P, Michelangeli V, et al.
Clin Endocrinol (Oxf)
. 2008 Mar;
69(4):648-52.
PMID: 18346211
Objective: There are conflicting data regarding the relationship between thyroid function and body mass index (BMI) in euthyroid subjects, and it is uncertain whether tobacco smoking modifies this relationship. The...
8.
Walsh J, Bremner A, Bulsara M, OLeary P, Leedman P, Feddema P, et al.
Clin Endocrinol (Oxf)
. 2006 Sep;
65(4):486-91.
PMID: 16984241
Objective: Overt hypothyroidism and hyperthyroidism are associated with hypertension, but it is uncertain whether the same is true of subclinical hypothyroidism and hyperthyroidism. Design, Subjects And Measurements: Cross-sectional study of...
9.
Walsh J, Bremner A, Bulsara M, OLeary P, Leedman P, Feddema P, et al.
Clin Endocrinol (Oxf)
. 2005 Dec;
63(6):670-5.
PMID: 16343102
Objective: It is uncertain whether subclinical hypothyroidism (SCH) is associated with hypercholesterolaemia, particularly in subjects with SCH and serum TSH < or = 10 mU/l. Design, Patients And Measurements: Cross-sectional...
10.
Walsh J, Bremner A, Bulsara M, OLeary P, Leedman P, Feddema P, et al.
Arch Intern Med
. 2005 Nov;
165(21):2467-72.
PMID: 16314542
Background: There have been few large epidemiological studies examining the association between thyroid dysfunction and cardiovascular disease. In particular, it is uncertain if subclinical hypothyroidism is a risk factor for...