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Peter Demant

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Recent Articles
1.
Berankova M, Holoubek J, Honig V, Matusova Z, Palus M, Salat J, et al.
J Neuroinflammation . 2025 Jan; 22(1):22. PMID: 39875898
Background: Tick-borne encephalitis (TBE) is the most common tick-borne viral infection in Eurasia. Outcomes range from asymptomatic infection to fatal encephalitis, with host genetics likely playing a role. BALB/c mice...
2.
Mrazek J, Mrazkova L, Mekadim C, Jarosikova T, Krayem I, Sohrabi Y, et al.
Appl Microbiol Biotechnol . 2024 Jan; 108(1):145. PMID: 38240984
Cutaneous leishmaniasis, a parasitic disease caused by Leishmania major, is a widely frequent form in humans. To explore the importance of the host gut microbiota and to investigate its changes...
3.
Quan L, Demant P
bioRxiv . 2023 Nov; PMID: 37986945
Interactions of large gene families are poorly understood. We found that human, mouse, and rat colon and lung cancer susceptibility genes, presently considered as separate gene families, were frequently pairwise...
4.
Krayem I, Sohrabi Y, Havelkova H, Gusareva E, Strnad H, cepickova M, et al.
Front Immunol . 2023 Aug; 14:1145269. PMID: 37600780
Leishmaniasis, a disease caused by parasites of spp., endangers more than 1 billion people living in endemic countries and has three clinical forms: cutaneous, mucocutaneous, and visceral. Understanding of individual...
5.
Krayem I, Sohrabi Y, Javorkova E, Volkova V, Strnad H, Havelkova H, et al.
Front Immunol . 2022 Feb; 12:760881. PMID: 35154069
Differences in frequencies of blood cell subpopulations were reported to influence the course of infections, atopic and autoimmune diseases, and cancer. We have discovered a unique mouse strain B10.O20 containing...
6.
Lipoldova M, Demant P
Front Immunol . 2021 Nov; 12:712688. PMID: 34721380
Inflammation is an integral part of defense against most infectious diseases. These pathogen-induced immune responses are in very many instances strongly influenced by host's sex. As a consequence, sexual dimorphisms...
7.
Bissahoyo A, Xie Y, Yang L, Pearsall R, Lee D, Elliott R, et al.
Genetics . 2019 Dec; 214(3):691-702. PMID: 31879319
The azoxymethane model of colorectal cancer (CRC) was used to gain insights into the genetic heterogeneity of nonfamilial CRC. We observed significant differences in susceptibility parameters across 40 mouse inbred...
8.
Kobets T, cepickova M, Volkova V, Sohrabi Y, Havelkova H, Svobodova M, et al.
Front Immunol . 2019 Jun; 10:1083. PMID: 31231359
Leishmaniasis is a serious health problem in many countries, and continues expanding to new geographic areas including Europe and USA. This disease, caused by parasites of spp. and transmitted by...
9.
Ochola D, Sharif R, Bedford J, Keefe T, Kato T, Fallgren C, et al.
Radiat Res . 2018 Nov; 191(1):67-75. PMID: 30398394
The risk of developing radiation-induced lung cancer differs between different strains of mice, but the underlying cause of the strain differences is unknown. Strains of mice also differ in how...
10.
Sohrabi Y, Volkova V, Kobets T, Havelkova H, Krayem I, Slapnickova M, et al.
Front Immunol . 2018 Feb; 9:130. PMID: 29467757
Interferon-induced GTPases [guanylate-binding proteins (GBPs)] play an important role in inflammasome activation and mediate innate resistance to many intracellular pathogens, but little is known about their role in leishmaniasis. We...