Peter D Heintzman
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Explore the profile of Peter D Heintzman including associated specialties, affiliations and a list of published articles.
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32
Citations
777
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Recent Articles
1.
Gilardet A, Lord E, Garcia G, Xenikoudakis G, Douka K, Wooller M, et al.
Mol Ecol Resour
. 2025 Feb;
:e14077.
PMID: 39912442
Large-scale DNA screening of palaeontological and archaeological collections remains a limiting and costly factor for ancient DNA studies. Several DNA extraction protocols are routinely used in ancient DNA laboratories and...
2.
Dolenz S, van der Valk T, Jin C, Oppenheimer J, Sharif M, Orlando L, et al.
Bioinformatics
. 2024 Jul;
40(7).
PMID: 38960861
Motivation: The alignment of sequencing reads is a critical step in the characterization of ancient genomes. However, reference bias and spurious mappings pose a significant challenge, particularly as cutting-edge wet...
3.
Dehasque M, Morales H, Diez-Del-Molino D, Pecnerova P, Chacon-Duque J, Kanellidou F, et al.
Cell
. 2024 Jun;
187(14):3531-3540.e13.
PMID: 38942016
A number of species have recently recovered from near-extinction. Although these species have avoided the immediate extinction threat, their long-term viability remains precarious due to the potential genetic consequences of...
4.
Dalen L, Heintzman P, Kapp J, Shapiro B
Science
. 2023 Oct;
382(6666):48-53.
PMID: 37797036
Although most ancient DNA studies have focused on the last 50,000 years, paleogenomic approaches can now reach into the early Pleistocene, an epoch of repeated environmental changes that shaped present-day...
5.
Williams J, Spanbauer T, Heintzman P, Blois J, Capo E, Goring S, et al.
Trends Ecol Evol
. 2023 May;
38(10):946-960.
PMID: 37230884
Ancient environmental DNA (aeDNA) data are close to enabling insights into past global-scale biodiversity dynamics at unprecedented taxonomic extent and resolution. However, achieving this potential requires solutions that bridge bioinformatics...
6.
Diez-Del-Molino D, Dehasque M, Chacon-Duque J, Pecnerova P, Tikhonov A, Protopopov A, et al.
Curr Biol
. 2023 Apr;
33(9):1753-1764.e4.
PMID: 37030294
Ancient genomes provide a tool to investigate the genetic basis of adaptations in extinct organisms. However, the identification of species-specific fixed genetic variants requires the analysis of genomes from multiple...
7.
Brown T, Rijal D, Heintzman P, Clarke C, Blankholm H, Hoeg H, et al.
PNAS Nexus
. 2023 Jan;
1(5):pgac209.
PMID: 36712342
Population size has increasingly been taken as the driver of past human environmental impact worldwide, and particularly in the Arctic. However, sedimentary ancient DNA (sedaDNA), pollen and archaeological data show...
8.
Garces-Pastor S, Coissac E, Lavergne S, Schworer C, Theurillat J, Heintzman P, et al.
Nat Commun
. 2022 Nov;
13(1):6559.
PMID: 36333301
The European Alps are highly rich in species, but their future may be threatened by ongoing changes in human land use and climate. Here, we reconstructed vegetation, temperature, human impact...
9.
Alsos I, Rijal D, Ehrich D, Karger D, Yoccoz N, Heintzman P, et al.
Sci Adv
. 2022 Sep;
8(39):eabo7434.
PMID: 36170372
What drives ecosystem buildup, diversity, and stability? We assess species arrival and ecosystem changes across 16 millennia by combining regional-scale plant sedimentary ancient DNA from Fennoscandia with near-complete DNA and...
10.
van der Valk T, Dehasque M, Chacon-Duque J, Oskolkov N, Vartanyan S, Heintzman P, et al.
iScience
. 2022 Aug;
25(8):104826.
PMID: 35992080
Woolly mammoths had a set of adaptations that enabled them to thrive in the Arctic environment. Many mammoth-specific single nucleotide polymorphisms (SNPs) responsible for unique mammoth traits have been previously...