Peter Brechlin
Overview
Explore the profile of Peter Brechlin including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
216
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Recent Articles
1.
Loginov D, Fiala J, Brechlin P, Kruppa G, Novak P
Biochim Biophys Acta Proteins Proteom
. 2021 Nov;
1870(2):140735.
PMID: 34742912
Methods of structural mass spectrometry have become more popular to study protein structure and dynamics. Among them, fast photochemical oxidation of proteins (FPOP) has several advantages such as irreversibility of...
2.
Loginov D, Fiala J, Chmelik J, Brechlin P, Kruppa G, Novak P
ACS Omega
. 2021 Jun;
6(22):14726.
PMID: 34124494
[This corrects the article DOI: 10.1021/acsomega.1c00732.].
3.
Loginov D, Fiala J, Chmelik J, Brechlin P, Kruppa G, Novak P
ACS Omega
. 2021 May;
6(15):10352-10361.
PMID: 34056188
Fast photochemical oxidation of proteins (FPOP) is a recently developed technique for studying protein folding, conformations, interactions, etc. In this method, hydroxyl radicals, usually generated by KrF laser photolysis of...
4.
Linker R, Brechlin P, Jesse S, Steinacker P, Lee D, Asif A, et al.
PLoS One
. 2009 Oct;
4(10):e7624.
PMID: 19865482
The identification of new biomarkers is of high interest for the prediction of the disease course and also for the identification of pathomechanisms in multiple sclerosis (MS). To specify markers...
5.
Uhrig M, Brechlin P, Jahn O, Knyazev Y, Weninger A, Busia L, et al.
BMC Med
. 2008 Dec;
6:38.
PMID: 19087254
Background: Alzheimer's disease (AD) is characterized by neurodegeneration and changes in cellular processes, including neurogenesis. Proteolytic processing of the amyloid precursor protein (APP) plays a central role in AD. Owing...
6.
Brechlin P, Jahn O, Steinacker P, Cepek L, Kratzin H, Lehnert S, et al.
Proteomics
. 2008 Sep;
8(20):4357-66.
PMID: 18814332
So far only the detection of 14-3-3 proteins in cerebrospinal fluid (CSF) is included in the diagnostic criteria for sporadic Creutzfeldt-Jakob disease (sCJD). However, this assay cannot be used for...
7.
Mollenhauer B, Steinacker P, Bahn E, Bibl M, Brechlin P, Schlossmacher M, et al.
Neurodegener Dis
. 2007 Jul;
4(5):366-75.
PMID: 17622779
Background: The measurement of biomarkers in cerebrospinal fluid (CSF) has gained increasing acceptance in establishing the diagnosis of some neurodegenerative diseases. Heart-type fatty acid-binding protein (H-FABP) was recently discovered in...
8.
Cepek L, Brechlin P, Steinacker P, Mollenhauer B, Klingebiel E, Bibl M, et al.
Dement Geriatr Cogn Disord
. 2006 Oct;
23(1):22-8.
PMID: 17068393
So far, only the detection of 14-3-3 proteins in cerebrospinal fluid (CSF) has been accepted as diagnostic criterion for Creutzfeldt-Jakob disease (CJD). However, this assay cannot be used for screening...
9.
Mollenhauer B, Trenkwalder C, von Ahsen N, Bibl M, Steinacker P, Brechlin P, et al.
Dement Geriatr Cogn Disord
. 2006 Aug;
22(3):200-8.
PMID: 16899997
Measurement of tau-protein and beta-amyloid(1-42 )(Abeta42) in cerebrospinal fluid (CSF) has gained increasing acceptance in the differential diagnosis of Alzheimer's disease. We investigated CSF tau-protein and Abeta42 concentrations in 73...
10.
Steinacker P, Schwarz P, Reim K, Brechlin P, Jahn O, Kratzin H, et al.
Mol Cell Biol
. 2005 Feb;
25(4):1339-46.
PMID: 15684385
The diagnosis of sporadic Creutzfeldt-Jakob disease (CJD) is based on typical clinical findings and is supported by a positive 14-3-3 Western blot of cerebrospinal fluid. However, it is not clear...