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Peter Adrian

Explore the profile of Peter Adrian including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 15
Citations 364
Followers 0
Related Specialties
Infectious Diseases
Microbiology
Allergy & Immunology
Top 10 Co-Authors
Shabir A Madhi
Keith P Klugman
Clare L Cutland
Locadiah Kuwanda
Sithembiso Velaphi
Alane Izu
Gaurav Kwatra
Clare Cutland
Ziyaad Dangor
Sanjay G Lala
Published In
J Infect Dis
Vaccine
Infect Immun
Lancet
Expert Rev Vaccines
Affiliations
Soon will be listed here.
Recent Articles
1.
Streptococcus pneumoniae colonization in pneumococcal vaccine-naïve human immunodeficiency virus-exposed infected and -uninfected South African children
Coelho Nunes M, Kim S, Zeldow B, Violari A, Dittmer S, Cassim H, et al.
Medicine (Baltimore) . 2020 Mar; 99(9):e19353. PMID: 32118776
Pneumococcal nasopharyngeal colonization is a pre-requisite for pneumococcal disease; the risk for pneumococcal disease is high in children born to women living with human immunodeficiency virus (HIV). We investigated pneumococcal...
2.
Strain Level Colonization Patterns during the First Year of Life
Wright M, McCorrison J, Gomez A, Beck E, Harkins D, Shankar J, et al.
Front Microbiol . 2017 Sep; 8:1661. PMID: 28932211
Pneumococcal pneumonia has decreased significantly since the implementation of the pneumococcal conjugate vaccine (PCV), nevertheless, in many developing countries pneumonia mortality in infants remains high. We have undertaken a study...
3.
Maternal HIV infection associated with reduced transplacental transfer of measles antibodies and increased susceptibility to disease
Jallow S, Cutland C, Masbou A, Adrian P, Madhi S
J Clin Virol . 2017 Aug; 94:50-56. PMID: 28759772
Background: Transplacental transfer of measles antibodies from mother to fetus is important in protecting against measles during early infancy. Changes in population immunity against measles in adults, including waning of...
4.
Correlates of protection of serotype-specific capsular antibody and invasive Group B Streptococcus disease in South African infants
Dangor Z, Kwatra G, Izu A, Adrian P, Cutland C, Velaphi S, et al.
Vaccine . 2015 Oct; 33(48):6793-9. PMID: 26478200
Background: Vaccinating pregnant women may prevent invasive Group B Streptococcus (GBS) disease in their young infants. In a low-middle income setting, we sought to determine an association between natural maternal...
5.
Association between maternal Group B Streptococcus surface-protein antibody concentrations and invasive disease in their infants
Dangor Z, Kwatra G, Izu A, Adrian P, Cutland C, Velaphi S, et al.
Expert Rev Vaccines . 2015 Sep; 14(12):1651-60. PMID: 26364978
Objectives: Group B Streptococcus (GBS) surface-proteins have been shown to be immunogenic and potential vaccine candidates. We aim to determine the association between maternal IgG antibodies to select GBS surface-proteins...
6.
HIV-1 Is Associated With Lower Group B Streptococcus Capsular and Surface-Protein IgG Antibody Levels and Reduced Transplacental Antibody Transfer in Pregnant Women
Dangor Z, Kwatra G, Izu A, Adrian P, van Niekerk N, Cutland C, et al.
J Infect Dis . 2015 Feb; 212(3):453-62. PMID: 25651843
Background: Human immunodeficiency virus (HIV)-exposed infants are at increased risk of invasive Group B Streptococcus (GBS) disease; however, the reason for this increased susceptibility has not been characterized. Methods: We...
7.
Inferior quantitative and qualitative immune responses to pneumococcal conjugate vaccine in infants with nasopharyngeal colonization by Streptococcus pneumoniae during the primary series of immunization
Madhi S, Violari A, Klugman K, Lin G, McIntyre J, von Gottberg A, et al.
Vaccine . 2011 Jul; 29(40):6994-7001. PMID: 21787822
Background: Heightened immunogenicity, measured one month after the primary series of pneumococcal conjugate vaccine (PCV), in African children was previously hypothesized to be due to increased rates of nasopharyngeal pneumococcal...
8.
Use of 2 pneumococcal common protein real-time polymerase chain reaction assays in healthy children colonized with Streptococcus pneumoniae
Rouphael N, Steyn S, Bangert M, Sampson J, Adrian P, Madhi S, et al.
Diagn Microbiol Infect Dis . 2011 Mar; 70(4):452-4. PMID: 21397430
Polymerase chain reaction (PCR) offers promise in pneumococcal diagnostics, but whether nasopharyngeal carriage causes false-positive results in people colonized with Streptococcus pneumoniae is unknown. We found in serum no positive...
9.
Effect of HIV infection status and anti-retroviral treatment on quantitative and qualitative antibody responses to pneumococcal conjugate vaccine in infants
Madhi S, Adrian P, Cotton M, McIntyre J, Jean-Philippe P, Meadows S, et al.
J Infect Dis . 2010 Jun; 202(3):355-61. PMID: 20583920
Serotype-specific antibody concentration and opsonophagocytic activity (OPA) were evaluated after 3 doses of pneumococcal conjugate vaccine. Groups included human immunodeficiency virus (HIV)-positive infants with CD4(+) cell percentages > or =25%...
10.
An unusual pneumococcal sequence type is the predominant cause of serotype 3 invasive disease in South Africa
Mothibeli K, du Plessis M, von Gottberg A, de Gouveia L, Adrian P, Madhi S, et al.
J Clin Microbiol . 2009 Nov; 48(1):184-91. PMID: 19889905
We reviewed pneumococcal serotype 3 cases reported from 2000 through 2005 to a laboratory-based surveillance system for invasive pneumococcal disease in South Africa. The prevalence of serotype 3 invasive isolates...