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Peter A Simmons

Explore the profile of Peter A Simmons including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 542
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Recent Articles
1.
Aragona P, Benitez-Del-Castillo J, Coroneo M, Mukherji S, Tan J, Vandewalle E, et al.
Clin Ophthalmol . 2020 Oct; 14:2951-2963. PMID: 33061281
Purpose: To compare the efficacy and safety of an artificial tear combining the polymers carboxymethylcellulose (CMC) and hyaluronic acid (HA), to a formulation of CMC alone in subjects with dry...
2.
Aragona P, Simmons P, Wang H, Wang T
Transl Vis Sci Technol . 2019 Nov; 8(6):2. PMID: 31695963
Purpose: To assess the physicochemical properties of hyaluronic acid (HA)-based artificial tears. Methods: The average molecular weight (MW) and polydispersion index (PDI) of HA in 18 commercially available artificial tears...
3.
Wallerstein A, Jackson W, Chambers J, Moezzi A, Lin H, Simmons P
Clin Ophthalmol . 2018 May; 12:839-848. PMID: 29765198
Purpose: To compare the efficacy and safety of a preservative-free, multi-ingredient formulation of carboxymethylcellulose 0.5%, hyaluronic acid 0.1%, and organic osmolytes (CMC-HA), to preservative-free carboxymethylcellulose 0.5% (CMC) in the management...
4.
Simmons P, Vehige J
Clin Ophthalmol . 2017 Oct; 11:1637-1642. PMID: 28979093
Purpose: Artificial tear formulations typically contain a water-soluble polymer to enhance residence time, moisture retention, and binding to the mucin coat of the ocular surface, which facilitate corneal healing. This...
5.
She Y, Li J, Xiao B, Lu H, Liu H, Simmons P, et al.
J Ocul Pharmacol Ther . 2015 Sep; 31(9):525-30. PMID: 26322539
Purpose: To evaluate effects of a novel multi-ingredient artificial tear formulation containing carboxymethylcellulose (CMC) and hyaluronic acid (HA) in a murine dry eye model. Methods: Dry eye was induced in...
6.
Simmons P, Liu H, Carlisle-Wilcox C, Vehige J
Clin Ophthalmol . 2015 May; 9:665-75. PMID: 25931807
Purpose: To evaluate and compare the efficacy and safety of two investigational artificial tear formulations (CHO-1 and CHO-2) containing carmellose sodium, hyaluronic acid at different concentrations, and osmoprotectants, with a...
7.
Simmons P, Carlisle-Wilcox C, Vehige J
Clin Ophthalmol . 2015 May; 9:657-64. PMID: 25931806
Background: Dry eye may be caused or exacerbated by deficient lipid secretion. Recently, lipid-containing artificial tears have been developed to alleviate this deficiency. Our study compared the efficacy, safety, and...
8.
Simmons P, Carlisle-Wilcox C, Chen R, Liu H, Vehige J
Clin Ther . 2015 Feb; 37(4):858-68. PMID: 25659956
Purpose: Dry eye disease is highly prevalent worldwide, causing discomfort and visual disturbances that can limit basic activities such as reading and driving. Although artificial tears represent first-line therapy, there...
9.
Madden L, Tomlinson A, Simmons P
Eye Contact Lens . 2013 Feb; 39(2):169-74. PMID: 23411993
Purpose: Many dry eye (DE) patients are sensitive to adverse environments where tear evaporation rate (TER) increases. Pilot study-A controlled environment chamber was used to determine the time of exposure...
10.
Tomlinson A, Madden L, Simmons P
Curr Eye Res . 2013 Jan; 38(2):229-36. PMID: 23294168
Purpose: Dry eye is often characterized by increased tear evaporation due to poor tear film quality, especially of the lipid component of the tear film. Using an environmental chamber to...