Peter A Doris
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Explore the profile of Peter A Doris including associated specialties, affiliations and a list of published articles.
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53
Citations
700
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Recent Articles
1.
Li K, Smith M, Blazier J, Kochan K, Wood J, Howe K, et al.
Genome Res
. 2024 Nov;
34(11):2081-2093.
PMID: 39516046
We report the construction and analysis of a new reference genome assembly for , the laboratory rat, a widely used experimental animal model organism. The assembly has been adopted as...
2.
Kalbfleisch T, Smith M, Ciosek J, Li K, Doris P
Physiol Genomics
. 2024 Sep;
56(12):807-818.
PMID: 39348459
The rat, , has provided an important model for investigation of a range of characteristics of biomedical importance. Here we survey the origins of this species, its introduction into laboratory...
3.
de Jong T, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, et al.
Cell Genom
. 2024 Mar;
4(4):100527.
PMID: 38537634
The seventh iteration of the reference genome assembly for Rattus norvegicus-mRatBN7.2-corrects numerous misplaced segments and reduces base-level errors by approximately 9-fold and increases contiguity by 290-fold compared with its predecessor....
4.
Dhande I, Zhu Y, Joshi A, Hicks M, Braun M, Doris P
Am J Physiol Renal Physiol
. 2023 Jul;
325(3):F317-F327.
PMID: 37439198
During development of the spontaneously hypertensive rat (SHR), several distinct but closely related lines were generated. Most lines are resistant to hypertensive renal disease. However, the SHR-A3 line (stroke-prone SHR)...
5.
de Jong T, Pan Y, Rastas P, Munro D, Tutaj M, Akil H, et al.
bioRxiv
. 2023 May;
PMID: 37214860
The seventh iteration of the reference genome assembly for -mRatBN7.2-corrects numerous misplaced segments and reduces base-level errors by approximately 9-fold and increases contiguity by 290-fold compared to its predecessor. Gene...
6.
Kalbfleisch T, Hussien AbouEl Ela N, Li K, Brashear W, Kochan K, Hillhouse A, et al.
Hypertension
. 2022 Nov;
80(1):138-146.
PMID: 36330812
Background: We report the creation and evaluation of a de novo assembly of the genome of the spontaneously hypertensive rat, the most widely used model of human cardiovascular disease. Methods:...
7.
Saha P, Mell B, Golonka R, Bovilla V, Abokor A, Mei X, et al.
Hypertension
. 2022 Aug;
79(10):2239-2249.
PMID: 35950503
Background: The spontaneously hypertensive rat (SHR) is extensively used to study hypertension. Gut microbiota dysbiosis is a notable feature in SHR for reasons unknown. Immunoglobulin A (IgA) is a major...
8.
de Jong T, Chen H, Brashear W, Kochan K, Hillhouse A, Zhu Y, et al.
Physiol Genomics
. 2022 May;
54(7):251-260.
PMID: 35543507
Rat genomic tools have been slower to emerge than for those of humans and mice and have remained less thorough and comprehensive. The arrival of a new and improved rat...
9.
Gray E, Patel S, Doris P, Hussain T
Front Pharmacol
. 2022 Feb;
12:778953.
PMID: 35197849
Clinical use of the combination therapy of the neprilysin inhibitor sacubitril and angiotensin II type 1 receptor blocker valsartan is known to be associated with albuminuria. Albuminuria is both a...
10.
Dhande I, Braun M, Doris P
Hypertension
. 2021 Nov;
78(6):1689-1700.
PMID: 34757770
The pathogenic links between elevated blood pressure and chronic kidney disease remain obscure. This article examines progress in population genetics and in animal models of hypertension and chronic kidney disease....