Perry D Moerland
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Explore the profile of Perry D Moerland including associated specialties, affiliations and a list of published articles.
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94
Citations
2455
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Recent Articles
1.
de Vries L, Jongejan A, Fortes J, Balesar R, Rozemuller A, Moerland P, et al.
Acta Neuropathol Commun
. 2025 Feb;
13(1):36.
PMID: 39972359
No abstract available.
2.
Chen J, McNamara N, Engelenburg H, Jongejan A, Wever D, Hopman K, et al.
Brain
. 2024 Dec;
PMID: 39718981
Multiple sclerosis (MS) is a highly heterogeneous disease with varying remyelination potential across individuals and between lesions. However, the molecular mechanisms underlying the potential to remyelinate remain poorly understood. In...
3.
Vegting Y, Jongejan A, Neele A, Claessen N, Sela G, Prange K, et al.
Nephrol Dial Transplant
. 2024 Dec;
PMID: 39694817
Background And Hypothesis: Kidney macrophage infiltration is a histological hallmark of vasculitic lesions and is strongly linked to disease activity in anti-neutrophil cytoplasmic antibodies (ANCA)-associated glomerulonephritis (AGN). The precise mechanisms...
4.
van Kampen A, Mahamune U, Jongejan A, van Schaik B, Balashova D, Lashgari D, et al.
Nat Commun
. 2024 Sep;
15(1):8117.
PMID: 39284801
Reproducibility of computational research is often challenging despite established guidelines and best practices. Translating these guidelines into practical applications remains difficult. Here, we present ENCORE, an approach to enhance transparency...
5.
Vegting Y, Hanford K, Jongejan A, Gajadin G, Versloot M, van der Bom-Baylon N, et al.
Atherosclerosis
. 2024 Aug;
397:118559.
PMID: 39186910
Background And Aims: Anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitides (AAV) is associated with an increased cardiovascular risk, particularly the myeloperoxidase AAV serotype (MPO-AAV). Distinct alterations in monocyte phenotypes may cause accelerated...
6.
van Bruggen J, Peters F, Mes M, Rietveld J, Cerretani E, Cretenet G, et al.
Blood Adv
. 2024 Jul;
8(17):4633-4646.
PMID: 39042920
Autologous T-cell-based therapies, such as chimeric antigen receptor (CAR) T-cell therapy, exhibit low success rates in chronic lymphocytic leukemia (CLL) and correlate with a dysfunctional T-cell phenotype observed in patients....
7.
de Vries L, Jongejan A, Fortes J, Balesar R, Rozemuller A, Moerland P, et al.
Acta Neuropathol Commun
. 2024 Apr;
12(1):68.
PMID: 38664739
Some individuals show a discrepancy between cognition and the amount of neuropathological changes characteristic for Alzheimer's disease (AD). This phenomenon has been referred to as 'resilience'. The molecular and cellular...
8.
Janssens G, Molenaars M, Herzog K, Grevendonk L, Remie C, Vervaart M, et al.
Nat Aging
. 2024 Apr;
4(5):681-693.
PMID: 38609524
Studies in preclinical models suggest that complex lipids, such as phospholipids, play a role in the regulation of longevity. However, identification of universally conserved complex lipid changes that occur during...
9.
van den Bosch A, van der Poel M, Fransen N, Vincenten M, Bobeldijk A, Jongejan A, et al.
Nat Commun
. 2024 Feb;
15(1):1667.
PMID: 38396116
Microglia nodules (HLA-DR cell clusters) are associated with brain pathology. In this post-mortem study, we investigated whether they represent the first stage of multiple sclerosis (MS) lesion formation. We show...
10.
Haselager M, van Driel B, Perelaer E, de Rooij D, Lashgari D, Loos R, et al.
Hemasphere
. 2023 Aug;
7(9):e938.
PMID: 37637994
Chronic lymphocytic leukemia (CLL) cells are highly dependent on microenvironmental cells and signals. The lymph node (LN) is the critical site of in vivo CLL proliferation and development of resistance...