Perihan Nalbant
Overview
Explore the profile of Perihan Nalbant including associated specialties, affiliations and a list of published articles.
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28
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1790
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Recent Articles
1.
Nanda S, Calderon A, Sachan A, Duong T, Koch J, Xin X, et al.
Nat Commun
. 2023 Dec;
14(1):8356.
PMID: 38102112
Rho GTPases play a key role in the spatio-temporal coordination of cytoskeletal dynamics during cell migration. Here, we directly investigate crosstalk between the major Rho GTPases Rho, Rac and Cdc42...
2.
Patwardhan R, Nanda S, Wagner J, Stockter T, Dehmelt L, Nalbant P
Mol Biol Cell
. 2023 Nov;
35(1):br1.
PMID: 37910204
Fibroblasts migrate discontinuously by generating transient leading-edge protrusions and irregular, abrupt retractions of a narrow trailing edge. In contrast, keratinocytes migrate persistently and directionally via a single, stable, broad protrusion...
3.
Nalbant P, Wagner J, Dehmelt L
Pflugers Arch
. 2023 Oct;
475(12):1439-1452.
PMID: 37851146
Cell contraction plays an important role in many physiological and pathophysiological processes. This includes functions in skeletal, heart, and smooth muscle cells, which lead to highly coordinated contractions of multicellular...
4.
Hensel A, Stahl P, Moews L, Konig L, Patwardhan R, Hoing A, et al.
iScience
. 2022 May;
25(6):104355.
PMID: 35601920
The unique threonine protease Tasp1 impacts not only ordered development and cell proliferation but also pathologies. However, its substrates and the underlying molecular mechanisms remain poorly understood. We demonstrate that...
5.
Kowalczyk M, Kamps D, Wu Y, Dehmelt L, Nalbant P
Chembiochem
. 2021 Dec;
23(4):e202100582.
PMID: 34897929
Cells process information via signal networks that typically involve multiple components which are interconnected by feedback loops. The combination of acute optogenetic perturbations and microscopy-based fluorescent response readouts enables the...
6.
Dorsch M, Kowalczyk M, Planque M, Heilmann G, Urban S, Dujardin P, et al.
Cell Rep
. 2021 Nov;
37(8):110056.
PMID: 34818551
Statins are among the most commonly prescribed drugs, and around every fourth person above the age of 40 is on statin medication. Therefore, it is of utmost clinical importance to...
7.
Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network
Kamps D, Koch J, Juma V, Campillo-Funollet E, Graessl M, Banerjee S, et al.
Cell Rep
. 2020 Dec;
33(9):108467.
PMID: 33264629
Local cell contraction pulses play important roles in tissue and cell morphogenesis. Here, we improve a chemo-optogenetic approach and apply it to investigate the signal network that generates these pulses....
8.
Nalbant P, Dehmelt L
Biol Chem
. 2018 Apr;
399(8):809-819.
PMID: 29664730
Cells need to process multifaceted external cues to steer their dynamic behavior. To efficiently perform this task, cells implement several exploratory mechanisms to actively sample their environment. In particular, cells...
9.
Graessl M, Koch J, Calderon A, Kamps D, Banerjee S, Mazel T, et al.
J Cell Biol
. 2017 Oct;
216(12):4271-4285.
PMID: 29055010
Rho GTPase-based signaling networks control cellular dynamics by coordinating protrusions and retractions in space and time. Here, we reveal a signaling network that generates pulses and propagating waves of cell...
10.
Jeruschke S, Jeruschke K, DiStasio A, Karaterzi S, Buscher A, Nalbant P, et al.
PLoS One
. 2015 Sep;
10(9):e0137043.
PMID: 26331477
Background: Glomerular podocytes are highly differentiated cells that are key components of the kidney filtration units. The podocyte cytoskeleton builds the basis for the dynamic podocyte cytoarchitecture and plays a...