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Pedro Beltran-Alvarez

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Citations 630
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Recent Articles
1.
Rodriguez-Barucg Q, Garcia A, Garcia-Merino B, Akinmola T, Okotie-Eboh T, Francis T, et al.
Environ Pollut . 2024 Sep; 362:124952. PMID: 39277126
This study investigates the effects of environmentally-relevant concentrations of fluoxetine (FLX, commercial name: Prozac) on wound healing. Pollution of water systems with pharmaceutical and personal care products, including antidepressants such...
2.
Gilbert E, Zagar A, Lopez-Darias M, Megia-Palma R, Lister K, Jones M, et al.
PLoS One . 2024 Mar; 19(3):e0300111. PMID: 38470891
Better understanding how organisms respond to their abiotic environment, especially at the biochemical level, is critical in predicting population trajectories under climate change. In this study, we measured constitutive stress...
3.
Feugere L, Bates A, Emagbetere T, Chapman E, Malcolm L, Bulmer K, et al.
PNAS Nexus . 2023 May; 2(5):pgad137. PMID: 37228511
Heat alters biology from molecular to ecological levels, but may also have unknown indirect effects. This includes the concept that animals exposed to abiotic stress can induce stress in naive...
4.
Barry A, Samuel S, Hosni I, Moursi A, Feugere L, Sennett C, et al.
Lab Chip . 2023 May; 23(11):2664-2682. PMID: 37191188
Arginine methylation is a post-translational modification that consists of the transfer of one or two methyl (CH) groups to arginine residues in proteins. Several types of arginine methylation occur, namely...
5.
Bilton L, Warren C, Humphries R, Kalsi S, Waters E, Francis T, et al.
Cancers (Basel) . 2022 Jul; 14(14). PMID: 35884550
Chromobox 2 (CBX2) is a chromatin-binding component of polycomb repressive complex 1, which causes gene silencing. CBX2 expression is elevated in triple-negative breast cancer (TNBC), for which there are few...
6.
Feugere L, Scott V, Rodriguez-Barucg Q, Beltran-Alvarez P, Wollenberg Valero K
J Therm Biol . 2021 Dec; 102:103114. PMID: 34863478
Aquatic organisms must cope with both rising and rapidly changing temperatures. These thermal changes can affect numerous traits, from molecular to ecological scales. Biotic stressors are already known to induce...
7.
Wollenberg Valero K, Garcia-Porta J, Irisarri I, Feugere L, Bates A, Kirchhof S, et al.
J Anim Ecol . 2021 Oct; 91(6):1163-1179. PMID: 34695234
Understanding the genomic basis of adaptation to different abiotic environments is important in the context of climate change and resulting short-term environmental fluctuations. Using functional and comparative genomics approaches, we...
8.
Marsden A, Riley D, Barry A, Khalil J, Guinn B, Kemp N, et al.
ACS Pharmacol Transl Sci . 2021 Oct; 4(5):1567-1577. PMID: 34661075
Protein arginine methyltransferases (PRMTs) catalyze the transfer of methyl groups to arginine residues in proteins. PRMT inhibitors are novel, promising drugs against cancer that are currently in clinical trials, which...
9.
Marsden A, Riley D, Birkett S, Rodriguez-Barucg Q, Guinn B, Carroll S, et al.
Amino Acids . 2021 Jun; 54(4):591-600. PMID: 34181092
Cardiovascular disease is the major cause of death worldwide. Extensive cardiovascular biomarkers are available using blood tests but very few, if any, investigations have described non-invasive tests for cardiovascular biomarkers...
10.
Samuel S, Barry A, Greenman J, Beltran-Alvarez P
Amino Acids . 2021 Jan; 53(4):489-506. PMID: 33404912
Despite intense research efforts, our pharmaceutical repertoire against high-grade brain tumours has not been able to increase patient survival for a decade and life expectancy remains at less than 16 ...