Payaningal R Somanath
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Explore the profile of Payaningal R Somanath including associated specialties, affiliations and a list of published articles.
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114
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2595
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Recent Articles
1.
Dutta S, Dutta S, Somanath P, Narayanan S, Wang X, Zhang D
Curr Issues Mol Biol
. 2025 Feb;
47(2).
PMID: 39996854
Cellular nucleosomes-the structural and functional units of chromatin-are inherently present in cells. During cellular damage or cell death, nucleosomes are released into circulation, either actively or passively. Once released, nucleosomes...
2.
Alfarhan M, Liu F, Matani B, Somanath P, Narayanan S
Cells
. 2025 Jan;
13(24).
PMID: 39768141
Diabetic retinopathy, a major cause of vision loss, is characterized by neurovascular changes in the retina. The lack of effective treatments to preserve vision in diabetic patients remains a significant...
3.
Vo J, La L, Anderson A, Alanazi A, Somanath P
Physiol Rep
. 2025 Jan;
13(1):e70192.
PMID: 39756822
Cancer is a complex disease with profound societal and economic impacts, especially in metastatic cases where treatment challenges arise due to the absence of reliable biomarkers and effective therapies. While...
4.
Zhu Y, Dutta S, Han Y, Choi D, Polverino F, Owen C, et al.
Redox Biol
. 2024 Dec;
79():103481.
PMID: 39721495
Emerging evidence suggests that lipid-laden macrophages (LLM) participate in lung damage in various clinical conditions. However, the mechanisms involved in LLM formation are not fully understood. In this study, we...
5.
Dutta S, Zhu Y, Almuntashiri S, Somanath P, Islam S, Zhi W, et al.
FASEB J
. 2024 Nov;
38(23):e70214.
PMID: 39612188
Extracellular histones are released in two major forms: free histones and nucleosomes (DNA-bound histones). However, little distinction has been made between these two forms of circulating extracellular histones. Our study...
6.
Dutta S, Zhu Y, Almuntashiri S, Peh H, Zuniga J, Zhang D, et al.
Am J Physiol Lung Cell Mol Physiol
. 2024 Nov;
328(1):L60-L74.
PMID: 39585242
Tissue inhibitor of metalloproteinases-1 (TIMP-1) is a physiologic inhibitor of the matrix metalloproteinases (MMPs), but little is known about the role of TIMP-1 in regulating the pathogenesis of influenza A...
7.
Shan S, Alanazi A, Han Y, Zhang D, Liu Y, Narayanan S, et al.
Biomedicines
. 2024 Sep;
12(9).
PMID: 39335566
Diabetic retinopathy (DR) is a leading cause of blindness, yet its molecular mechanisms are unclear. Extracellular vesicles (EVs) contribute to dysfunction in DR, but the characteristics and functions of vitreous...
8.
Bokhtia R, Pham A, Gupta K, Warang S, Venugopal N, Shakuja R, et al.
Chembiochem
. 2024 Jul;
25(20):e202400376.
PMID: 39073289
New Ursolic Acid (UA) conjugates were synthesized using optimized synthetic protocols through the molecular hybridization approach at C-3 and C-28. This resulted in the targeted molecules being produced in good...
9.
Alanazi A, Selim M, Yendamuri M, Zhang D, Narayanan S, Somanath P
Tissue Barriers
. 2024 Jul;
:2386183.
PMID: 39072526
Diabetes Mellitus presents a formidable challenge as one of the most prevalent and complex chronic diseases, exerting significant strain on both patients and the world economy. It is recognized as...
10.
Alanazi A, Shan S, Narayanan S, Somanath P
Life (Basel)
. 2024 Jul;
14(7).
PMID: 39063636
Background: Diabetic retinopathy (DR) is a leading cause of vision loss, with complex mechanisms. The study aimed to comprehensively explore vitreous humor of diabetic and non-diabetic individuals, paving the way...