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Pawel Grochecki

Explore the profile of Pawel Grochecki including associated specialties, affiliations and a list of published articles. Areas
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Articles 13
Citations 50
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Recent Articles
1.
Filarowska-Jurko J, Grochecki P, Gibula-Tarlowska E, Listos J, Kedzierska E, Socha J, et al.
Molecules . 2025 Jan; 29(24. PMID: 39770104
The N-methyl-D-aspartate (NMDA) glutamate receptor is a major target of ethanol, and it is implicated in learning and memory formation, and other cognitive functions. Glycine acts as a co-agonist for...
2.
Socha J, Grochecki P, Marszalek-Grabska M, Skrok A, Smaga I, Slowik T, et al.
Int J Mol Sci . 2024 Jun; 25(12). PMID: 38928357
Cannabidiol (CBD), a phytocannabinoid, appeared to satisfy several criteria for a safe approach to preventing drug-taking behavior, including opioids. However, most successful preclinical and clinical results come from studies in...
3.
Socha J, Grochecki P, Smaga I, Jastrzebska J, Wronikowska-Denysiuk O, Marszalek-Grabska M, et al.
Int J Mol Sci . 2024 Jan; 25(2). PMID: 38256113
Children with fetal alcohol spectrum disorders (FASDs) demonstrate deficits in social functioning that contribute to early withdrawal from school and delinquency, as well as the development of anxiety and depression....
4.
Kotlinska J, Grochecki P, Michalak A, Pankowska A, Kochalska K, Suder P, et al.
Biomolecules . 2023 Oct; 13(10). PMID: 37892131
Repeated maternal separation (MS) is a useful experimental model in rodents for studying the long-term influence of early-life stress on brain neurophysiology. In our work, we assessed the effect of...
5.
Grochecki P, Smaga I, Wydra K, Marszalek-Grabska M, Slowik T, Kedzierska E, et al.
Int J Mol Sci . 2023 Feb; 24(3). PMID: 36768263
Treatment of Post-Traumatic Stress Disorder (PTSD) is complicated by the presence of drug use disorder comorbidity. Here, we examine whether conditioned fear (PTSD model) modifies the rewarding effect of mephedrone...
6.
Grochecki P, Smaga I, Surowka P, Marszalek-Grabska M, Kalaba P, Dragacevic V, et al.
Int J Mol Sci . 2022 Sep; 23(18). PMID: 36142621
Maternal separation (MS) is a key contributor to neurodevelopmental disorders, including learning disabilities. To test the hypothesis that dopamine signaling is a major factor in this, an atypical new dopamine...
7.
Filarowska-Jurko J, Komsta L, Smaga I, Surowka P, Marszalek-Grabska M, Grochecki P, et al.
Int J Mol Sci . 2022 May; 23(10). PMID: 35628160
Adverse early life experiences are associated with an enhanced risk for mental and physical health problems, including substance abuse. Despite clinical evidence, the mechanisms underlying these relationships are not fully...
8.
Grochecki P, Smaga I, Marszalek-Grabska M, Lopatynska-Mazurek M, Slowik T, Gibula-Tarlowska E, et al.
Int J Mol Sci . 2022 Feb; 23(4). PMID: 35216236
Mephedrone, a synthetic cathinone, is widely abused by adolescents and young adults. The aim of this study was to determine: (i) whether prior mephedrone exposure would alter ethanol reward and...
9.
Marszalek-Grabska M, Smaga I, Surowka P, Grochecki P, Slowik T, Filip M, et al.
Int J Mol Sci . 2021 Aug; 22(15). PMID: 34360704
The activation of the endocannabinoid system controls the release of many neurotransmitters involved in the brain reward pathways, including glutamate. Both endocannabinoid and glutamate systems are crucial for alcohol relapse....
10.
Gibula-Tarlowska E, Korz V, Lopatynska-Mazurek M, Chlopas-Konowalek A, Grochecki P, Kalaba P, et al.
Behav Brain Res . 2021 May; 410:113326. PMID: 33940050
Perinatal alcohol exposure can lead to fetal alcohol spectrum disorders (FASD), usually first diagnosed in childhood, that are characterized by hyperactivity, impulsivity and learning and memory disability, among others. To...