Pawan Dhar
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Explore the profile of Pawan Dhar including associated specialties, affiliations and a list of published articles.
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10
Citations
64
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Recent Articles
1.
Joshi K, Goyal S, Grover S, Jamal S, Singh A, Dhar P, et al.
BMC Bioinformatics
. 2017 Feb;
17(Suppl 19):515.
PMID: 28155653
Background: Tar DNA binding protein 43 (TDP-43) hyperphosphorylation, caused by Casein kinase 1 (CK-1) protein isoforms, is associated with the onset and progression of Amyotrophic Lateral Sclerosis (ALS). Among the...
2.
Laskar S, K S, Bhattacharyya M, Nair A, Dhar P, Bhattacharyya S
Mol Cell Biol
. 2014 Nov;
35(2):437-50.
PMID: 25384977
The epigenetic writer Sir2 maintains the heterochromatin state of chromosome in three chromosomal regions, namely, the silent mating type loci, telomeres, and the ribosomal DNA (rDNA). In this study, we...
3.
Tun K, Menghini M, DAndrea L, Dhar P, Tanaka H, Giuliani A
Curr Comput Aided Drug Des
. 2011 May;
7(3):206-13.
PMID: 21599620
The apparently paradoxical lack of correlation between the huge increase in the discovery of new potential drug targets made possible by the post-genomic sciences and new drugs development has stimulated...
4.
Zhu H, Wu Y, Huang S, Sun Y, Dhar P
IEEE Trans Nanobioscience
. 2005 Aug;
4(2):141-8.
PMID: 16117022
Cellular automata are an important modeling paradigm for studying the dynamics of large, parallel systems composed of multiple, interacting components. However, to model biological systems, cellular automata need to be...
5.
Meng T, Somani S, Dhar P
In Silico Biol
. 2005 Feb;
4(3):293-309.
PMID: 15724281
Mathematical modeling is a powerful approach for understanding the complexity of biological systems. Recently, several successful attempts have been made for simulating complex biological processes like metabolic pathways, gene regulatory...
6.
Zhu H, Sun Y, Rajagopal G, Mondry A, Dhar P
Biomed Eng Online
. 2004 Sep;
3:29.
PMID: 15339335
Background: Many arrhythmias are triggered by abnormal electrical activity at the ionic channel and cell level, and then evolve spatio-temporally within the heart. To understand arrhythmias better and to diagnose...
7.
Zhu H, Pang P, Sun Y, Dhar P
BMC Bioinformatics
. 2004 Jun;
5:85.
PMID: 15222901
Background: The behaviors of cells in metazoans are context dependent, thus large-scale multi-cellular modeling is often necessary, for which cellular automata are natural candidates. Two related issues are involved in...
8.
Dhar P
Trends Biotechnol
. 2004 Mar;
22(3):103-4.
PMID: 15043043
Cytokinesis is the last ritual of a dividing cell. Determining the position and horizon of the cell furrow is important for equal distribution of cytoplasmic content between the two daughter...
9.
Dhar P, Meng T, Somani S, Ye L, Sairam A, Chitre M, et al.
Bioinformatics
. 2004 Feb;
20(8):1319-21.
PMID: 14871872
Unlabelled: The intracellular environment of a cell hosts a wide variety of enzymatic reactions, diffusion events, molecular binding, polymerization and metabolic channeling. To transform these biological events into a computational...
10.
Zhu H, Huang S, Dhar P
Bioessays
. 2003 Dec;
26(1):68-72.
PMID: 14696042
As a result of the time- and context-dependency of gene expression, gene regulatory and signaling pathways undergo dynamic changes during development. Creating a model of the dynamics of molecular interaction...